American children live in a variety of family structures throughout their childhoods. Such instability in family arrangements is common and has important demonstrated implications for short-term child outcomes. However, it is not known whether family instability experienced in childhood has enduring health consequences across the life course. Using demographic, social, and biological data from the National Longitudinal Study of Adolescent to Adult Health, we investigate the family stress model, testing the relationship between parental family instability in childhood and four biological markers of health in young adulthood. This is the first study to examine whether the accumulation of family change in childhood leaves a lasting physiological residue. While family instability is associated with poorer short-term behavioral and socioeconomic outcomes as documented in previous research, we find no evidence of deleterious young adult health consequences. These findings are robust across different measures of physiological health risk and types of family transitions.
AdamEmma K.Chase-LansdaleP. Lindsay. 2002. “Home Sweet Home(s): Parental Separations, Residential Moves, and Adjustment Problems in Low-income Adolescent Girls.” Developmental Psychology38(5):792–805.
2.
AmatoPaul R.PattersonSarah E.2017. “The Intergenerational Transmission of Union Instability in Early Adulthood.” Journal of Marriage and Family79(3):723–38.
3.
AntonovskyAaron. 1996. “The Salutogenic Model as a Theory to Guide Health Promotion.” Health Promotion International11(1):11–18.
4.
AntonovskyAaronSouraniTalma. 1988. “Family Sense of Coherence and Family Adaptation.” Journal of Marriage and the Family50(1):79–92.
5.
BelkaidYasmineHandTimothy W.2014. “Role of the Microbiota in Immunity and Inflammation.” Cell157(1):121–41.
6.
BohrAdam D.LaursonKellyMcQueenMatthew B.2016. “A Novel Cutoff for the Waist-to-height Ratio Predicting Metabolic Syndrome in Young American Adults.” BMC Public Health16(1):295. doi:0.1186/s12889-016-2964-6.
7.
BrownSusan L.StykesJ. BartManningWendy D.2016. “Trends in Children’s Family Instability, 1995–2010.” Journal of Marriage and Family78(5):1173–83.
8.
BzostekSharon H.BeckAudrey N.2011. “Familial Instability and Young Children’s Physical Health.” Social Science & Medicine73(2):282–92.
9.
CavanaghShannon E.CrisseySarah R.RaleyR. Kelly. 2008. “Family Structure History and Adolescent Romance.” Journal of Marriage and Family70(3):698–714.
10.
CavanaghShannon E.FombyPaula. 2012. “Family Instability, School Context, and the Academic Careers of Adolescents.” Sociology of Education85(1):81–97.
11.
CavanaghShannon E.HustonAletha C.2006. “Family Instability and Children’s Early Problem Behavior.” Social Forces85(1):551–81.
CherlinAndrew J.1978. “Remarriage as an Incomplete Institution.” American Journal of Sociology84(3):634–50.
14.
ColdwellJoannePikeAlisonDunnJudy. 2006. “Household Chaos—Links with Parenting and Child Behaviour.” Journal of Child Psychology and Psychiatry47(11):1116–22.
15.
ColemanMarilynGanongLawrenceFineMark. 2000. “Reinvestigating Remarriage: Another Decade of Progress.” Journal of Marriage and Family62(4):1288–307.
16.
CooperCarey E.OsborneCynthia A.BeckAudrey N.McLanahanSara S.2011. “Partnership Instability, School Readiness, and Gender Disparities.” Sociology of Education84(3):246–59.
17.
Del GiudiceMarcoEllisBruce J.ShirtcliffElizabeth A.2011. “The Adaptive Calibration Model of Stress Responsivity.” Neuroscience and Biobehavioral Reviews35(7):1562–92.
18.
EdgeMichael D.RamelWivekaDrabantEmily M.KuoJanice R.ParkerKaren J.GrossJames J.2009. “For Better or Worse? Stress Inoculation Effects for Implicit but Not Explicit Anxiety.” Depression and Anxiety26(9):831–37.
19.
ElderGlen H.CaspiAvshalom. 1988. “Economic Stress in Lives: Developmental Perspectives.” Journal of Social Issues44(4):25–45.
20.
EllisBruce J.GiudiceMarco Del. 2014. “Beyond Allostatic Load: Rethinking the Role of Stress in Regulating Human Development.” Development and Psychopathology26(1):1–20.
21.
FelittiVincent J.AndaRobert F.NordenbergDaleWilliamsonDavid F.SpitzAlison M.EdwardsValerieKossMary P.MarksJames S.1998. “Relationship of Childhood Abuse and Household Dysfunction to Many of the Leading Causes of Death in Adults: The Adverse Childhood Experiences (ACE) Study.” American Journal of Preventive Medicine14(4):245–58.
22.
FombyPaulaBosickStacey J.2013. “Family Instability and the Transition to Adulthood.” Journal of Marriage and Family75(5):1266–87.
23.
FombyPaulaCherlinAndrew J.2007. “Family Instability and Child Well-being.” American Sociological Review72(2):181–204.
24.
FombyPaulaMollbornStefanieSennottChristie A.2010. “Race/ethnic Differences in Effects of Family Instability on Adolescents’ Risk Behavior.” Journal of Marriage and Family72(2):234–53.
25.
GemsDavidPartridgeLinda. 2008. “Stress-response Hormesis and Aging: ‘That Which Does Not Kill Us Makes Us Stronger.’”Cell Metabolism7(3):200–203.
26.
GraefeDeborah RoempkeLichterDaniel T.1999. “Life Course Transitions of American Children: Parental Cohabitation, Marriage, and Single Mother-hood.” Demography36(2):205–217.
27.
GunnarMegan R.QuevedoKarina. 2007. “The Neurobiology of Stress and Development.” Annual Review of Psychology58(1):145–73.
28.
HarrisKathleen Mullan. 2010. “An Integrative Approach to Health.” Demography47(1):1–22.
29.
HernandezDaphne C.PresslerEmilyDoriusCassandraMitchellKatherine Stamps. 2014. “Does Family Instability Make Girls Fat? Gender Differences between Instability and Weight.” Journal of Marriage and Family76(1):175–90.
30.
Holt-LunstadJulianneSmithTimothy B.LaytonJ. Bradley. 2010. “Social Relationships and Mortality Risk: A Meta-analytic Review.” PLoS Medicine7(7):e1000316. doi:doi.org/10.1371/journal.pmed.1000316.
31.
HostinarCamelia E.GunnarMegan R.2013. “The Developmental Effects of Early Life Stress: An Overview of Current Theoretical Frameworks.” Current Directions in Psychological Science22(5):400–406.
32.
HusseyJon M.NguyenQuynh C.WhitselEric A.RichardsonLiana J.HalpernCarolyn TuckerGordon-LarsenPennyTaborJoyce W.EntzelPamela P.HarrisKathleen Mullan. 2015. “The Reliability of In-home Measures of Height and Weight in Large Cohort Studies: Evidence from Add Health.” Demographic Research32(1):1081–98.
33.
IrwinMichael R.ColeSteven W.2011. “Reciprocal Regulation of the Neural and Innate Immune Systems.” Nature Reviews: Immunology11(9):625–32.
34.
KellyJoan B.EmeryRobert E.2003. “Children’s Adjustment Following Divorce: Risk and Resilience Perspectives.” Family Relations52(4):352–62.
35.
KreiderRose M.LofquistDaphne A.2014. Adopted Children and Stepchildren: 2010. Current Population Reports P20-572. Washington, DC: U.S. Census Bureau.
36.
LeeDohoonMcLanahanSara S.2015. “Family Structure Transitions and Child Development: Instability, Selection, and Population Heterogeneity.” American Sociological Review80(4):738–63.
37.
LyonsDavid M.ParkerKaren J.2007. “Stress Inoculation-induced Indications of Resilience in Monkeys.” Journal of Traumatic Stress20(4):424–33.
38.
MacrìSimoneWürbelHanno. 2007. “Effects of Variation in Postnatal Maternal Environment on Maternal Behaviour and Fear and Stress Responses in Rats.” Animal Behaviour73(1):171–84.
39.
MagnusonKatherineBergerLawrence M.2009. “Family Structure States and Transitions: Associations with Children’s Well-being during Middle Childhood.” Journal of Marriage and Family71(3):575–91.
40.
McCubbinHamilton I.PattersonJoan M.1983. “The Family Stress Process: The Double ABCX Model of Adjustment and Adaptation.” Marriage & Family Review6(1/2):7–37.
41.
McDadeThomas W.MetzgerMolly W.ChyuLauraDuncanGreg J.GarfieldCraigAdamEmma K.2014. “Long-term Effects of Birth Weight and Breastfeeding Duration on Inflammation in Early Adulthood.” Proceedings of the Royal Society B: Biological Sciences281(1784):20133116. doi:10.1098/rspb.2013.3116.
42.
McEwenBruce S.LasleyElizabeth Norton. 2002. The End of Stress as We Know It. Washington, DC: Joseph Henry.
43.
MillerGregory E.ChenEdithFokAlexandra K.WalkerHopeLimAlvinNichollsErin F.ColeSteveKoborMichael S.2009. “Low Early-life Social Class Leaves a Biological Residue Manifested by Decreased Glucocorticoid and Increased Proinflammatory Signaling.” Proceedings of the National Academy of Sciences106(34):14716–21.
44.
MillerGregory E.LachmanMargie E.ChenEdithGruenewaldTara L.KarlamanglaArun S.SeemanTeresa E.2011. “Pathways to Resilience: Maternal Nurturance as a Buffer against the Effects of Childhood Poverty on Metabolic Syndrome at Midlife.” Psychological Science22(12):1591–99.
45.
MitchellColterHobcraftJohnMcLanahanSara S.SiegelSusan RutherforsBergArthurBrooks-GunnJeanneGarfinkelIrwinNottermanDaniel. 2014. “Social Disadvantage, Genetic Sensitivity, and Children’s Telomere Length.” Proceedings of the National Academy of Sciences111(16):5944–49.
46.
MitchellColterMcLanahanSara S.HobcraftJohnBrooks-GunnJeanneGarfinkelIrwinNottermanDaniel. 2015. “Family Structure Instability, Genetic Sensitivity, and Child Well-being.” American Journal of Sociology120(4):1195–225.
47.
NguyenQuynh C.TaborJoyce W.EntzelPamela P.LauYanSuchindranChirayathHusseyJon M.HalpernCarolyn T.HarrisKathleen MullanWhitselEric A.2011. “Discordance in National Estimates of Hypertension among Young Adults.” Epidemiology22(4):532–41.
48.
OsborneCynthiaBergerLawrence M.MagnusonKatherine. 2012. “Family Structure Transitions and Changes in Maternal Resources and Well-being.” Demography49(1):23–47.
49.
OsborneCynthiaMcLanahanSara S.2007. “Partnership Instability and Child Well-being.” Journal of Marriage and Family69(4):1065–83.
50.
ProvencalNadineMassartRenaudNemodaZsofiaSuomiStephen. 2016. “Alterations in DNA Methylation and Hydroxymethylation due to Parental Care in Rhesus Macaques.” Pp. 165–90 in Epigenetics and Neuroendocrinology, edited by SpenglerD.ChamE. Binder.Switzerland: Springer.
51.
RichardsonLiana J.HusseyJon M.StrutzKelly L.2011. “Origins of Disparities in Cardiovascular Disease: Birth Weight, Body Mass Index, and Young Adult Systolic Blood Pressure in the National Longitudinal Study of Adolescent Health.” Annals of Epidemiology21(8):598–607.
52.
SchetterChristine DunkelDolbierChristyn. 2011. “Resilience in the Context of Chronic Stress and Health in Adults.” Social and Personality Psychology Compass5(9):634–52.
53.
SchmeerKammi K.2012. “Family Structure and Obesity in Early Childhood.” Social Science Research41(4):820–32.
54.
SeemanTeresa E.SingerBurton H.RoweJohn W.HorwitzRalph I.McEwenBruce S.1997. “Price of Adaptation—Allostatic Load and Its Health Consequences: Macarthur Studies of Successful Aging.” Archives of Internal Medicine157(19):2259–68.
55.
ShaperoBenjamin G.HamiltonJessica L.StangeJonathan P.LiuRichard T.AbramsonLyn Y.AlloyLauren B.2015. “Moderate Childhood Stress Buffers against Depressive Response to Proximal Stressors: A Multi-wave Prospective Study of Early Adolescents.” Journal of Abnormal Child Psychology43(8):1403–13.
56.
SingerBurton H.RyffCarol D.2001. New Horizons in Health: An Integrative Approach. Washington, DC: National Academies Press.
57.
SteptoeAndrew. 2012. “Socioeconomic Status, Inflammation, and Immune Function.” Pp. 234–53 in The Oxford Handbook of Psychoneuroimmunology, edited by SegerstromS. C.Oxford, UK: Oxford University Press.
58.
TaylorShelley E.KemenyMargaret E.ReedGeoffrey M.BowerJulienne E.GruenewaldTara L.2000. “Psychological Resources, Positive Illusions, and Health.” American Psychologist55(1):99–109.
59.
TaylorShelley E.RepettiRena L.SeemanTeresa E.1997. “Health Psychology: What Is an Unhealthy Environment and How Does It Get under the Skin?” Annual Review of Psychology48(1):411–47.
60.
ThoitsPeggy A.1995. “Stress, Coping, and Social Support Processes: Where Are We? What Next?” Journal of Health and Social Behavior35(Extra Issue):53–79.
61.
ThoitsPeggy A.2010. “Stress and Health: Major Findings and Policy Implications.” Journal of Health and Social Behavior51(Supp.):S41–53.
62.
ThompsonRoss A.2014. “Stress and Child Development.” Future of Children24(1):41–60.
63.
VespaJonathanLewisJamie M.KreiderRose M.2013. America’s Families and Living Arrangements: 2012. Current Population Reports P20-570. Washington, DC: U.S. Department of Commerce.
64.
WhitselEric A.CuthbertsonCarmen C.TaborJoyce W.PotterAlan J.WenerMark H.Killeya-JonesLay A.HarrisKathleen Mullan. 2012. Add Health Wave IV Documentation: Measures of Inflammation and Immune Function. Chapel Hill, NC: Carolina Population Center.
65.
WickramaKandauda A. S.LorenzFrederick O.CongerRand D.1997. “Parental Support and Adolescent Physical Health Status: A Latent Growth-curve Analysis.” Journal of Health and Social Behavior38(2):149–63.
66.
WuLawrence L.1996. “Effects of Family Instability, Income, and Income Instability on the Risk of a Premarital Birth.” American Sociological Review61(3):386–406.
67.
WuLawrence L.MartinsonBrian C.1993. “Family Structure and the Risk of a Premarital Birth.” American Sociological Review58(2):210–32.
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