Co-occurring drug use among U.S.-born Latinas is underexamined. This study examines the relationship between polydrug use patterns and social inequality among low-income Mexican American women. Data stems from 199 Mexican American adult women collected during the follow-up period of Proyecto SALTO, a longitudinal cohort study. Latent class analysis (LCA) identified patterns of past month’s marijuana, amphetamine, cocaine, and heroin use. Age-adjusted multinomial logistic regressions were conducted between covariates and latent classes. The LCA identified three classes: Non/Low-Use, 60.30% (n = 120); Marijuana Use, 27.64% (n = 55); and Polydrug Use, 12.06% (n = 24). Marijuana and Polydrug Use classes had lower socioeconomic status indicators compared to the Non/Low-Use group. Though our sample’s drug use remains high compared to the general population, the largest class was Non/Low-Use. Low socioeconomic status and fractured family relationships were found to increase susceptibility for marijuana and polydrug use. Recognizing and addressing socioeconomic conditions is critical for tailored interventions.
AgrawalA.LynskeyM. T.MaddenP. A.BucholzK. K.HeathA. C. (2007). A latent class analysis of illicit drug abuse/dependence: Results from the national epidemiological survey on alcohol and related conditions. Addiction, 102(1), 94–104. https://doi.org/10.1111/j.1360-0443.2006.01630.x
2.
AiA. L.LeeJ. (2018). Childhood abuse, religious involvement, and lifetime substance use disorders among Latinas nationwide. Substance Use & Misuse, 53(13), 2099–2111. https://doi.org/10.1080/10826084.2018.1455701
3.
BaileyK.TrevillionK.GilchristG. (2019). What works for whom and why: A narrative systematic review of interventions for reducing post-traumatic stress disorder and problematic substance use among women with experiences of interpersonal violence. Journal of Substance Abuse Treatment, 99, 88–103. https://doi.org/10.1016/j.jsat.2018.12.007
4.
BanksD. E.BelloM. S.CrichlowQ.LeventhalA. M.Barnes-NajorJ. V.ZapolskiT. C. (2020). Differential typologies of current substance use among Black and White high-school adolescents: A latent class analysis. Addictive Behaviors, 106, Article 106356. https://doi.org/10.1016/j.addbeh.2020.106356
5.
Centers for Diease Control and Prevention. (2022). Use of selected substances in the past month among people aged 12 years and over, by age, sex, and race and Hispanic origin: United States, selected years 2002–2019.
6.
CepedaA.NowotnyK.M.FrankebergerJ.RamirezE.RodriguezV.E.PerdueT.ValdezA. (2020). Examination of multilevel domains of minority stress: Implications for drug use and mental and physical health among Latina women who have sex with women and men. PLOS One, 15(3), e0230437. https://doi.org/10.1371/journal.pone.0230437
7.
CepedaA.RamirezE.FrankebergerJ.NowotnyK.M.ValdezA. (2021). Nondisclosure of IPV Victimization Among Disadvantaged Mexican American Young Adult Women. In LopezVPaskoL (Eds.), Latinas in the Criminal Justice System (pp. 60–82). New York, NY: New York University Press.
8.
CepedaA.Saint OngeJ.NowotnyK. M.ValdezA. (2016). Associations Between Long-Term Gang Membership and Informal Social Control Processes, Drug Use, and Delinquent Behavior Among Mexican American Youth. International Journal of Offender Therapy and Comparative Criminology, 60(13), 1532–1548. https://doi.org/10.1177/0306624X155849
9.
CervantesR. C.DuenasN.ValdezA.KaplanC. (2006). Measuring violence risk and outcomes among Mexican American adolescent females. Journal of Interpersonal Violence, 21(1), 24–41. https://doi.org/10.1177/0886260505281602
10.
ConnellC. M.GilreathT. D.AklinW. M.BrexR. A. (2010). Social-ecological influences on patterns of substance use among non-metropolitan high school students. American Journal of Community Psychology, 45(1–2), 36–48. https://doi.org/10.1007/s10464-009-9289-x
11.
ConybeareD.BeharE.SolomonA.NewmanM. G.BorkovecT. (2012). The PTSD checklist—Civilian version: Reliability, validity, and factor structure in a nonclinical sample. Journal of Clinical Psychology, 68(6), 699–713. https://doi.org/10.1002/jclp.21845
12.
CookeA. C.KnightK. R.MiaskowskiC. (2019). Patients’ and clinicians’ perspectives of co-use of cannabis and opioids for chronic non-cancer pain management in primary care. International Journal of Drug Policy, 63, 23–28. https://doi.org/10.1016/j.drugpo.2018.09.002
13.
DashG. F.MartinN. G.AgrawalA.LynskeyM. T.SlutskeW. S. (2021). Typologies of illicit drug use in mid-adulthood: A quasi-longitudinal latent class analysis in a community-based sample of twins. Addiction, 116(5), 1101–1112. https://doi.org/10.1111/add.15225
14.
de JongeM. C.BukmanA. J.van LeeuwenL.OnrustS. A.KleinjanM. (2022). Latent classes of substance use in young adults–A systematic review. Substance Use & Misuse, 57(5), 769–785. https://doi.org/10.1080/10826084.2022.2040029
EvansE. A.GrellaC. E.WashingtonD. L.UpchurchD. M. (2017). Gender and race/ethnic differences in the persistence of alcohol, drug, and poly-substance use disorders. Drug and Alcohol Dependence, 174, 128–136. https://doi.org/10.1016/j.drugalcdep.2017.01.021
17.
FogelmanN.TateM.WemmS.SullivanL.HartR.VaceyE.FoxH. C.SinhaR. (2024). Substance use patterns, quantities, and associated risk factors in women with polysubstance misuse. Addiction Biology, 29(4), 1–12. https://doi.org/10.1111/adb.13390
18.
GaddD.HendersonJ.RadcliffeP.Stephens-LewisD.JohnsonA.GilchristG. (2019). The dynamics of domestic abuse and drug and alcohol dependency. British Journal of Criminology, 59(5), 1035–1053. https://doi.org/10.1093/bjc/azz011
19.
GoldbergD. P.GaterR.SartoriusN.UstunT. B.PiccinelliM.GurejeO.RutterC. (1997). The validity of two versions of the GHQ in the WHO study of mental illness in general health care. Psychological Medicine, 27(1), 191–197. https://doi.org/10.1017/s0033291796004242
20.
Gonzalez-BarreraA.LopezM. H. (2013). A demographic portrait of Mexican-origin Hispanics in the United States. Pew Hispanic Center.
21.
GoodwinS. R.MoskalD.MarksR. M.ClarkA. E.SquegliaL. M.RocheD. J. O. (2022). A scoping review of gender, sex and sexuality differences in polysubstance use in adolescents and adults. Alcohol and Alcoholism, 57(3), 292–321. https://doi.org/10.1093/alcalc/agac006
22.
HawkinsJ. D.CatalanoR. F.MillerJ. Y. (1992). Risk and protective factors for alcohol and other drug problems in adolescence and early adulthood: Implications for substance abuse prevention. Psychological Bulletin, 112(1), 64–105. https://doi.org/10.1037/0033-2909.112.1.64
23.
HuangH.CanoM.TrepkaM. J.SheehanD. M.SanchezM.RojasP.De La RosaM. (2021). Neighborhood and health-related outcomes: A study of adult Latinas of Caribbean and South and Central American descent in Miami. Journal of Ethnic & Cultural Diversity in Social Work, 30(4), 341–363. https://doi.org/10.1080/15313204.2019.1703127
LanzaS. T.DziakJ. J.HuangL.WagnerA. T.CollinsL. M. (2015). LCA stata plugin users’ guide (Version 1.2). University Park: The Methodology Center, Penn State.
26.
LubkeG. H.MuthénB. (2005). Investigating population heterogeneity with factor mixture models. Psychological Methods, 10(1), 21–39. https://doi.org/10.1037/1082-989X.10.1.21
27.
MelchiorL. A.HubaG.BrownV. B.RebackC. J. (1993). A short depression index for women. Educational and Psychological Measurement, 53(4), 1117–1125. https://doi.org/10.1177/0013164493053004024
28.
MoustafaA. A.ParkesD.FitzgeraldL.UnderhillD.GaramiJ.Levy-GigiE.StrameckiF.ValikhaniA.FrydeckaD.MisiakB. (2021). The relationship between childhood trauma, early-life stress, and alcohol and drug use, abuse, and addiction: An integrative review. Current Psychology, 40(2), 579–584. https://doi.org/10.1007/s12144-018-9973-9
29.
MuthénL. K.MuthénB. O. (2012) Mplus Version 7 user’s guide (Vol. 10). Muthén & Muthén.
30.
Noe-BustamanteL.LopezM. H.KrogstadJ. M. (2020). US Hispanic population surpassed 60 million in 2019, but growth has slowed.
31.
NowotnyK. M.ValdezA.CepedaA. (2023). Syndemic Profiles for HIV, Hepatitis C, and Sextually Transmitted Infections Among Mexican American Women Formerly Affiliated with Youth Street Gangs. AIDS and Behavior, 27, 388–399. https://doi.org/10.1007/s10461-022-03773-8
32.
NylundK. L.AsparouhovT.MuthénB. O. (2007). Deciding on the number of classes in latent class analysis and growth mixture modeling: A Monte Carlo simulation study. Structural Equation Modeling: A Multidisciplinary Journal, 14(4), 535–569. https://doi.org/10.1080/10705510701575396
33.
PalmerA.ScottN.DietzeP.HiggsP. (2020). Motivations for crystal methamphetamine-opioid co-injection/co-use amongst community-recruited people who inject drugs: A qualitative study. Harm Reduction Journal, 17(1), 1–6. https://doi.org/10.1186/s12954-020-00360-9
34.
PinedoM. (2019). A current re-examination of racial/ethnic disparities in the use of substance abuse treatment: Do disparities persist?Drug and Alcohol Dependence, 202, 162–167. https://doi.org/10.1016/j.drugalcdep.2019.05.017
35.
SchneiderK. E.O'RourkeA.WhiteR. H.ParkJ. N.MusciR. J.KilkennyM. E.ShermanS. G.AllenS. T. (2020). Polysubstance use in rural West Virginia: Associations between latent classes of drug use, overdose, and take-home naloxone. International Journal of Drug Policy, 76, Article 102642. https://doi.org/10.1016/j.drugpo.2019.102642
36.
SchneiderK. E.ParkJ. N.AllenS. T.WeirB. W.ShermanS. G. (2019). Patterns of polysubstance use and overdose among people who inject drugs in Baltimore, Maryland: A latent class analysis. Drug and Alcohol Dependence, 201, 71–77. https://doi.org/10.1016/j.drugalcdep.2019.03.026
37.
StricklandJ. C.SmithM. A. (2014). The effects of social contact on drug use: Behavioral mechanisms controlling drug intake. Experimental and Clinical Psychopharmacology, 22(1), 23–34. https://doi.org/10.1037/a0034669
38.
TuckerJ. S.HuangW.Green JrH. D.PollardM. S. (2021). Patterns of substance use and associations with mental, physical, and social functioning: A latent class analysis of a national sample of US adults ages 30–80. Substance Use & Misuse, 56(1), 131–139. https://doi.org/10.1080/10826084.2020.1843059
39.
ValdezA. (2005). Mexican American Girls and Gangs: Beyond Risk. New York, NY: Palgrave MacMillan.
40.
VegaW. A.RodriguezM. A.GruskinE. (2009). Health disparities in the Latino population. Epidemiologic Reviews, 31(1), 99–112. https://doi.org/10.1093/epirev/mxp008
