The effects of different stages of periodontal therapy on salivary pseudocholinesterase (PCE) activity in patients with periodontitis were determined by use of a spectrophotometric method. The mean PCE activity in whole saliva was 17.95 U/L in the pre-treatment phase, 4.67 U/L after scaling and oral hygiene instructions, and 1.93 U/L following surgical procedures. It was observed that the mean salivary PCE activity in patients with periodontitis showed a tendency to decrease in both phases of treatment, and PCE levels at the end of periodontal therapy were similar to those of healthy subjects.
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References
1.
Brown, S.S.; Kalow, W.; Pilz, W.; Whittaker, M.; and Woronick, C.L. (1981): Plasma Cholinesterases. In: Advances in Clinical Chemistry, Vol. 22, New York: Academic Press, pp. 1-123.
2.
Chatonnet, A. and Lockridge, O. (1989): Comparison of Butyrylcholinesterase and Acetylcholinesterase , Biochem J260 :625-634.
3.
Chauncey, H.H. (1961): Salivary Enzymes, J Am Dent Assoc63:361-368.
4.
Ellman, G.L.; Courtney, K.D.; Andres, V.; and Feath-Erstone, R.M. (1961): A New and Rapid Colorimetric Determination of Acetylesterase Activity, Biochem Pharmacol7 :88-95.
5.
Huntsberger, D.V. and Billingsley, P. (1973): Elements of Statistical Inference, Boston: Allyn and Bacon, Inc., pp. 184-187.
6.
Lisanti, V.F. (1960): Hydrolytic Enzymes in Periodontal Tissues, Ann NY Acad Sci85:461-466.
7.
Makinen, K.K. (1966): Studies on Oral Enzymes 1. Fractionation and Characterization of Aminopeptidases of Human Saliva, Acta Odontol Scand24:579-604.
8.
Nakamura, M. and Slots, J. (1983): Salivary Enzymes. Origin and Relationship to Periodontal Diseases, J Periodont Res18 :559-569.
9.
Pigman, W. and Reid, A.J. (1952): The Organic Compounds and Enzymes of Human Saliva , JAm Dent Assoc45:325-368.
10.
Ryhanen, R.J.J. (1983): Pseudocholinesterase Activity in Some Human Body Fluids, Gen Pharmacol14:459-460.
11.
Ryhanen, R.; Narhi, M.; Puhakainen, C.; Hanninen, O.; and Kontturi-Narhi, V. (1983): Pseudocholinesterase Activity and Its Origin in Human Oral Fluid, J Dent Res62 :20-23.
12.
Vorhaus, L.J. and Kark, R.M. (1953): Serum Cholinesterase in Health and Disease, Am J Med14:707-719.
13.
Winer, R.A.; O'Donnell, L.J.; Chauncey, H.H.; and McNamara, T.F. (1970): Enzyme Activity in Periodontal Disease, J Periodontol41:449-456.
14.
Yamalik, N.; Özer, N.; Çağlayan, F.; and Cağlayan, G. (1990): Determination of Pseudocholinesterase Activity in the Gingival Crevicular Fluid, Saliva and Serum from Patients with Juvenile Periodontitis and Rapidly Progressive Periodontitis, J Dent Res69:87-89.
15.
Zambon, J.J.; Nakamura, M.; and Slots, J. (1985): Effect of Periodontal Therapy on Salivary Enzymatic Activity, J Periodont Res20:652-659.
