The purpose of this paper is to enumerate and describe the oral complications that are associated with salivary gland dysfunction. The significance of these oral problems and their related adverse impact on the patient's quality of life are presented. Palliative and therapeutic agents and regimens are discussed, and a suggested protocol for managing the deleterious oral sequelae of salivary gland dysfunction is outlined.
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References
1.
BRENMANH.S.; KATZP.; SCHWARTZH.; and WEISW.W. (1986): Salivary Production in Xerostomic Patients Using the SAL™ System, J Dent Res65: 310, Abst. No. 1273 (AADR).
2.
BRINERW.W.; GROSSMANE.; BUCKNERR.Y.; REBITSKYT.E.; SETSERR.E.; and EBERTM.L. (1986): Effect of Chlorhexidine Gluconate Mouthrinse on Plaque Bacteria, J Periodont Res (Suppl): 44–52.
3.
BROWNL.R.; DREIZENS.; HANDLERS.; and JOHNSTOND.A. (1975): Effect of Radiation-induced Xerostomia on Human Oral Microflora, J Dent Res54: 740–750.
4.
DEL REGATOJ.A. (1939): Dental Lesions Observed After Roentgen Therapy in Cancer of the Buccal Cavity, Pharynx and Larynx, Am J Roentgenol Radiat Ther Nuclear Med42: 404–410.
5.
DREIZENS.; BROWNL.R.; DALEYE.; and DRANEJ.B. (1977): Prevention of Xerostomia-related Dental Caries in Irradiated Cancer Patients, J Dent Res56: 99–104.
6.
DREIZENS.; BROWNL.R.; HANDLERS.; and LEVYB.M. (1976): Radiation-induced Xerostomia in Cancer Patients: Effect on Salivary and Serum Electrolytes, Cancer38: 273–278.
7.
EDWARDSSONS.; BIRKHEDD.; and MEJAREB. (1977): Acid Production from Lycasin®, Maltitol, Sorbitol and Xylitol by Oral Streptococci and Lactobacilli, Acta Odontol Scand35: 257–263.
8.
FoxP.C.; VAN DER VENP.F.; SONIESB.C.; WEIFFENBACHJ.M.; and BAUMB.J. (1985): Xerostomia: Evaluation of a Symptom with Increasing Significance, J Am Dent Assoc110: 519–525.
9.
FoxP.C.; VAN DER VENP.F.; BAUMB.J.; and MANDELI.D. (1986): Pilocarpine for the Treatment of Xerostomia Associated with Salivary Gland Dysfunction, Oral Surg61: 243–248.
10.
FRANKR.M.; HERDLEYJ.; and PHILIPPEE. (1965): Acquired Dental Defects and Salivary Gland Lesions After Irradiation for Carcinoma, J Am Dent Assoc70: 868–883.
11.
GROSSMANE.; REITERG.; STURZENBERGERO.P.; DE LA ROSAM.; DICKINSONT.D.; FERRETTIG.A.; LUDLUMG.E.; and MECKELA.H. (1986): Six-month Study of the Effects of a Chlorhexidine Mouthrinse on Gingivitis in Adults, J Perio Res (Suppl): 33–43.
12.
HORIA.A. and KEYESP.H. (1964): Vinyl Applicators for As-sessing Drugs in the Treatment of Caries and Periodontal Disease in the Hamster, J Dent Res43: 152.
13.
KATZS. (1982): The Use of Fluoride and Chlorhexidine for the Prevention of Radiation Caries, J Am Dent Assoc104: 164–170.
14.
KEYESP.H.; WRIGHTW.E.; and HOWARDS.A. (1978): The Use of Phase-contrast Microscopy and Chemotherapy in the Diagnosis and Treatment of Periodontal Lesions — An Initial Report, Quint Int Dent J9: 51–56.
15.
NEWBRUNE., HOOVERC.I.; and RYDERM.I. (1984): Bactericidal Action of Bicarbonate Ion on Selected Periodontal Pathogenic Microorganisms, J Periodontal55: 658–667.
16.
SHANNONI.L.; McCRARYB.R.; and STARCKEE.N. (1977): A Saliva Substitute for Use of Xerostomic Patients Undergoing Radiotherapy to the Head and Neck, Oral Surg44: 656–661.
17.
SHIPL.I.; ANDERSONF.W.; and OSHEROFFB.S. (1960): Development and Clinical Investigation of a New Oral Anesthetic for Acute and Chronic Oral Lesions, Oral Surg13: 630–636.
18.
SJÖGRENH. (1933): Kenntnis der Keratoconjunctivitis Sicca (Keratitis Filiformis bei Hypofunktion der Tranendrusen), Acta Ophthalmol11(Suppl 2): 1.
19.
SILVERMANS.Jr. (1986): Infections and Sexually Transmitted Diseases: Implications for Dental Public Health, J Pub Hlth Dent46: 7–12.
20.
SILVERMANS.Jr.; MIGLIORATIC.A.; LOZADA-NURF.; GREENSPAND.; and CONANTM.A. (1986): Oral Findings in People with or at High Risk for AIDS: A Study of 375 Ho-mosexual Males, J Am Dent Assoc112: 187–192.
21.
WESCOTTW.B.; STARCKEE.N.; and SHANNONI.X. (1975): Chemical Protection Against Post Irradiation Dental Caries, Oral Surg40: 709–719.
22.
WOLINSKYL.E. and LOTTT. (1986): Effects of the Organic Salts Sodium Chloride, Sodium Bicarbonate and Magnesium Sulfate Upon the Growth and Motility of Treponema vincentii, J Periodontal57: 172–175.
23.
WRIGHTW.E.; MORROWI.L.; WOLFR.O.; and GALLELLIJ.F. (1980): Effect of Fluoride Mouthrinse on Salivary Flow in Xerostomic Subjects, IADR Prog & Abst59A: No. 756.
24.
WRIGHTW.E.; HALLERJ.M.; HARLOWS.A.; and PIZZOP.A. (1985): An Oral Disease Prevention Program for Patients Receiving Radiation and Chemotherapy, J Am Dent Assoc110: 43–47.
