In vivo Bovine Enamel Remineralization and Fluoride Uptake from two Dentifrices Containing Different Fluoride Concentrations

Abstract

In this study, the differences in lesion remineralization and fluoride uptake after brushing with a 300 ppm F or a 1000 ppm F dentifrice (as NaF) were investigated.

Twenty volunteers with partial dentures in their lower jaws were divided into two groups. Bovine enamel slabs with artificial lesions were mounted in the dentures. After a test period of six weeks, the slabs were taken out and analyzed. There was no statistically significant difference between the two groups, in F-uptake and susceptibility of the enamel to demineralization, although the findings favored the 1000 ppm F toothpaste. The microradiograms in the 300 ppm F group showed lesions more pronounced than those in the 1000 ppm group.

The present study cannot support the presumption that the fluoride content of regular NaF dentifrices can be lowered to 300 ppm F without undesirable effects on lesion arrest and remineralization.

Get full access to this article

View all access options for this article.

References

Arends, J. ; Nelson, D.G.A. ; Dijkman, A.G. ; and Jonge-Bloed, W.L. (1984): Effects of Various Fluorides on Enamel Structure and Chemistry. In: Cariology Today , B. Guggenheim , Ed., Basel: Karger, pp. 245-258.

Bruun, C. ; Givskov, H. ; and Thylstrup, A. (1984): Whole Saliva Fluoride after Toothbrushing with NaF and MFP Dentifrices with Different F Concentrations, Caries Res 18:282-288.

Ekstrand, J. and Koch, G. (1980): Systemic Fluoride Absorption Following Gel Application , J Dent Res 59:1067.

Ekstrand, J. ; Koch, G. ; Lindgren, L.E. ; and Petersson, L.G. (1981): Pharmacokinetics of Fluoride Gels in Children and Adults, Caries Res 15:213-220.

Ekstrand, J. ; Koch, G. ; and Petersson, L.G. (1983): Plasma Fluoride Concentration in Pre-school Children after Ingestion of Fluoride Tablets and Toothpaste, Caries Res 17:379-384.

Fejerskov, 0.; Thylstrup, A. ; and Larsen, M.J. (1981): Rational Use of Fluorides in Caries Prevention. A Concept Based on Possible Cariostatic Mechanisms, Acta Odontol Scand 39 :241-249.

Forsman, B. (1974): Studies on the Effect of Dentifrices with Low Fluoride Content, Community Dent Oral Epidemiol 2:166-175.

Gelhard, T.B.F.M. and Arends, J. (1984): Microradiography of in vivo Remineralized Lesions in Human Enamel, J Biol Buccale 12:59-65.

Groeneveld, A. and Arends, J. (1975): Influence of pH and Demineralization Time on Mineral Content, Thickness of Surface Layer and Depth of Artificial Caries Lesions , Caries Res 9 :36-44.

10.

Koch, G. ; Petersson, L.G. ; Kling, E. ; and Kling, L. (1982): Effect of 250 and 1000 ppm Fluoride Dentifrice on Caries, Swed Dent J 6:233-238.

11.

Koulourides, T. ; Phantumvanit, P. ; Munksgaard, E.C. ; and Housch, T. (1974): An Intraoral Model Used for Studies of Fluoride Incorporation in Enamel, J Oral Pathol 3:185-196.

12.

Marthaler, T.M. (1984): Explanations for Changing Patterns of Disease in the Western World. In: Cariology Today , B. Guggenheim , Ed., Basel: Karger, pp. 13-23.

13.

Mallon, D.E. and Mellberg, J.R. (1984): Inhibition of Caries Lesion Formation by an MFP Dentifrice and APF Solution, Pediatr Dent 6:230-234.

14.

Mobley, M.J. (1981): Fluoride Uptake from in situ Brushing with a SnF2 and a NaF Dentifrice, J Dent Res 60:1943-1948.

15.

Reed, M.V. (1973): Clinical Evaluation of Three Concentrations of Sodium Fluoride in Dentifrices, J Am Dent Assoc 87:1401-1403.

16.

Reintsema, J. ; Schuthof, J. ; and Arends, J. (1985): An in vivo Investigation of the Fluoride Uptake in Partially Demineralized Human Enamel from Several Different Dentifrices , J Dent Res 64:19-23.

17.

Stookey, G.K. ; Schemehorn, B.R. ; Whetstone, B.L. ; Wood, G.D. ; and Walton, G.V. (1985): In situ Fluoride Uptake from Fluoride Dentifrices , J Dent Res 64:900-903.

18.

Ten Cate, J.M. (1984): The Effect of Fluoride on Enamel De- and Remineralization in vitro and in vivo. In: Cariology Today , B. Guggenheim , Ed., Basel: Karger, pp. 231-236.

19.

Ten Cate, J.M. and Rempt, H.E. (1986): Comparison of the in vivo Effect of a 0 and 1500 ppm F MFP Paste on Fluoride Uptake, Acid Resistance and Lesion Remineralization , Caries Res 20 :193-201.

20.

Ten Cate, J.M. and Simons, Y. (1986): Efficacies of Toothpastes with Different Fluoride Concentrations, Determined by "pH-cycling". In: Factors Relating to Demineralization and Remineralization of the Teeth, S.A. Leach , Ed., London: IRL, pp. 35-43.