This paper provides an anatomical overview of the dentin-predentin complex and its permeability. An unique anatomical feature of this complex is the presence of dentinal tubules which extend peripherally from the odontoblast-predentin junction throughout the thickness of the tissue. The permeability of dentin is a consequence of the presence of these tubules. Thus, this review concentrates on the anatomy of dentinal tubules and, in particular, on those studies which in the last decade have increased our knowledge of this anatomy. The structure, size, and number of dentinal tubules and the relationship of these features to the permeability of the tissue are discussed. This is followed by a description of the contents of dentinal tubules, with particular emphasis being paid to the literature concerning the extent of the odontoblast process.
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