The fluoride in successive layers of dentin (from 3-6 μm were removed per etch) has been measured following topical or iontophoretic application of 2% aqueous sodium fluoride to coronal exposed dentin of freshly extracted human third molar teeth. The fluoride contents of the topical and iontophoresed first etches were, respectively, 12 and 22-31 times greater than that of control (untreated) teeth. Similarly, the fourth etches were 12 and 50-70 times greater, and the seventh (last sampled) etches were 5 and 28-41 times greater. There was no apparent change in acid solubility of the dentin as its fluoride content varied under the conditions of this study. This is the first report studying the fluoride content of extremely thin layers of dentin successively removed by acid etch and relating topical to iontophoretic uptake.
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References
1.
Brannstrom, M.: A Hydrodynamic Mechanism in the Transmission of Pain-Producing Stimuli Through the Dentine. In: Sensory Mechanism in Dentine, D.J. Anderson, Ed., Oxford: Pergamon Press, 1963, p. 73.
2.
Ehrlich, J.; Hochman, N.; Gedalia, I.; and Tal, M.: Residual Fluoride Concentrations and Scanning Electron Microscopic Examination of Root Surfaces of Human Teeth after Topical Application of Fluoride in vivo , J Dent Res54:897-900, 1975.
3.
Gangarosa, L. and Park, N.H.: Practical Considerations in Iontophoresis of Fluoride for Desensitizing Hypersensitive Dentin, J Prosthet Dent39:173-178, 1978.
4.
Gedalia, I.; Brayer, L.; Kalter, N.; Richter, M.; and Stabholz, A.: The Effect of Fluoride and Strontium Application on Dentin: in vivo and in vitro Studies, J Periodontol49:269-272, 1978.
5.
Gindler, E.M. and King, L.D.: Rapid Colorimetric Determination of Calcium in Biologic Fluids with Methylthymol Blue, Am J Clin Pathol58:376-382, 1972.
6.
Greenhill, J.D. and Pashley, D.H.: The Effects of Desensitizing Agents on the Hydraulic Conductance of Human Dentin, in vitro, J Dent Res60:686-698, 1981.
7.
Harris, R.: Iontophoresis. In: Therapeutic Electricity and Ultraviolet Radiation, 2nd ed., S. Licht, Ed., New Haven, CT: E. Licht, 1967, pp. 156-178.
8.
Hoyt, W.H. and Bibby, B.G.: Use of Sodium Fluoride for Desensitizing Dentin, JADA30:1372, 1943.
Lefkowitz, W. and Bodecker, C.F.: Sodium Fluoride, Its Effect on the Dental Pulp, Ann Dent3:141-146, 1945.
11.
Lefkowitz, W.: Pulp Response to Ionization, J Prosthet Dent12:966-976, 1962.
12.
Lefkowitz, W.; Burdick, H.C.; and Moore, D.L.: Desensitization of Dentin by Bioelectric Induction of Secondary Dentin , J Prosthet Dent13:940-949, 1963.
13.
Lukomsky, E.H.: Fluorine Therapy for Exposed Dentin and Alveolar Atrophy, J Dent Res20:649-658, 1941.
14.
Manning, M.M.: A New Approach to Desensitization of Cervical Dentin, Dent Survey37:731-734, 1961.
15.
Maurice, C.G. and Schour, I.: Effects of Sodium Fluoride Upon the Pulp of the Rat Molar, J Dent Res35:69-82, 1956.
16.
Murthy, K.S.; Talim, S.T.; and Singh, I.: A Comparative Evaluation of Topical Application and Iontophoresis of Sodium Fluoride for Desensitization of Hypersensitive Dentin, Oral Surg36:448-458, 1973.
17.
Pashley, D.H.; Livingston, M.J.; and Outhwaite, W.C.: Dentin Permeability: Changes Produced by Iontophoresis, J Dent Res57:77-82, 1978.
18.
Penney, D.A. and Karlsson, U.L.: Fast Desensitization of Tooth Roots by Topically Applied SnF2 and SrCl2 in Dogs, Arch Orad Biol21:339-347, 1976.
19.
Rovelstad, G.H. and ST. John, W.E.: The Condition of the Young Dental Pulp after the Application of Sodium Fluoride to Freshly Cut Dentin, JADA39:670-682, 1949.
20.
Sandoval, E. and Shannon, I.L.: Stannous Fluoride and Dentin Solubility, Texas Rep Biol Med27:111-116, 1969.
21.
Sausen, R.E.: Electrophoresis in Dentin with Radioactive Calcium, J Dent Res34:12-18, 1955.
22.
Scott, H.M., Jr.: Reductions of Sensitivity by Electrophoresis, J Dent Child29:225-241, 1962.
23.
Selvig, K.A.: Effect of Fluoride on the Acid Solubility of Human Dentine, Arch Oral Biol13:1297-1310, 1968 .
24.
Stanley, H.; White, C.; and McCray, L.: The Rate of Tertiary (Reparative) Dentine Formation in the Human Tooth , Oral Surg21: 579-589, 1966.
25.
Stowell, E.C.: Ion Penetration Through Teeth as Influenced by an Electrostatic Field , J Dent Res40:739-740, 1961.
26.
Taves, D.R.: Determination of Submicromolar Concentrations of Fluoride in Biological Samples , Talanta15:1015-1023, 1968 .
27.
Trautz, O.R.: Crystalline Organization of Dental Mineral. In: Structural and Chemical Organization of Teeth, Vol. II, A.E.W. Miles, Ed., New York: Academic Press, 1967, pp. 165-200.
28.
Walton, R.E.; Leonard, L.A.; Sharawy, M.; and Gangarosa, L.P.: Effects on Pulp and Dentin of Iontophoresis of Sodium Fluoride on Exposed Roots in Dogs, Oral Surg48 :545-557, 1979.
29.
Zadok, J.; Gedalia, I.; Weinman, J.; and Daphni, L.: Fluoride Uptake by Root Dentin after Immersion in 2% NaF Solution with Iontophoresis , J Dent Res55:310, 1976.
