Restricted accessResearch articleFirst published online 1983-07
Increases in Fluoride,Calcium,and Phosphate in Dental Plaque Resulting from the Use of a Mineralizing Mouthrinse Containing Urea and Monofluorophosphate
A mouthrinse used ten times over a four-day period increased the concentration of acid-extractable fluoride in immature plaque by 320%, calcium by 190%, and phosphate by 97%. Corresponding increases in mature plaque were smaller, yet significant. Diffusion of the ions from plaque was restricted, and hence a prolonged caries-inhibitory effect can be expected.
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References
1.
Hardwick, J.L. and Leach, S.A.: The Fluoride Content of Dental Plaque, Arch Oral Biol (Suppl):151-158, 1962.
2.
Dawes, C. and Jenkins, G.N.: Some Inorganic Constituents of Dental Plaque and Their Relationship to Early Calculus Formation and Caries, Arch Oral Biol7:161-172, 1962.
3.
Tatevossian, A.; Jenkins, G.N.; and Edgar, W.M.: Local Effect of Therapeutic Agents on Plaque Composition, J Dent Res54B:34-39, 1975.
4.
Hassell, T.M. ; Gabathuler, H.; and Muhlemann, H.R.: Telemetric Recording of Fluoride in the Interdental Area, Helv Odont Acta15:36-41, 1971.
5.
Tatevossian, A.: The Local Effect of Rinses on Plaque Composition: 2. Distribution and Retention of 0.02 M NaF in the Aqueous and Residual Phases, Helv Odont Acta17:51, 1973.
6.
Wycoff, S.J. ; Morris, M.E.; and Newbrun, E.: The Effect of Mouthrinse Containing Calcium Glycerophosphate on the Chemical Composition and Development of Plaque in Humans, J Dent Res59:23-28, 1980.
7.
Tatevossian, A. and Jenkins, G.N.: Changes in Plaque Phosphate Levels During Ingestion of Sugar and Sugar with Added Phosphate, J Dent Res48:1115, 1969.
8.
Ashley, F.P. and Wilson, R.F.: Effect of Sweets Supplemented with Dicalcium Phosphate on Dental Plaque Composition, Caries Res11:336-344, 1977.
9.
Pearce, E.I.F. : The Artificial Mineralization of Dental Plaque . In: The Environment of the Teeth. Frontiers of Oral Physiology , Vol. 3, Ferguson, D.B., Ed., Basel:Karger, 1981, pp. 108-124.
10.
Schamschula, R.G.; Adkins, B.L.; Barmes , D.E.; Charlton, G.; and Davey, B.G.: WHO Study of Dental Caries Etiology in Papua, New Guinea, Geneva: World Health Organization, 1978, pp. 38-66.
11.
Pearce, E.I.F. : Effect of Plaque Mineralization on Experimental Dental Caries, Caries Res16:460-471, 1982.
12.
CHEN, P.S.; TORIBARA, T.Y.; and WARNER, H.: Micro-determination of Phosphorus, Anal Chem 28:1756-1758, 1956. 13. LOWRY, O.H.; ROSEBROUGH, N.J.; FARR, A.L.; and RAN-DALL, R.J.: Protein Measurement with the Folin Phenol Reagent, J Biol Chem 193:265-275, 1951.
13.
Regolati, B. : Ammonia and Urea in Oral Pathophysiology - A Literature Review, Helv Odont Acta15(Suppl. VII): 139-146,1971.
14.
Frostell, G. : Studies on the Ammonia Production and the Ureolytic Activity of Dental Plaque Material, Acta Odontol Scand18:29-65, 1960.
15.
Stephan, R.M. and Hemmens, E.S.: Studies of Changes in pH Produced by Pure Cultures of Oral Micro-organisms. II. Comparison of Different Micro-organisms and Different Substrates, J Dent Res26:25-33, 1947.
Pearce, E.I.F. and Jenkins, G.N.: The Decomposition of Monofluorophosphate by Enzymes in Whole Human Saliva, Arch Oral Biol22:405-407, 1977.
18.
Eilberg, R.G. ; Judy, K.; Iovino , E.; Kornfeld, P.; Phelan, J.; and Ellison, R.: Relationship Between Plaque Mineralization in vitro and Calculus Formation in vivo, J Dent Res52:45-48, 1973.
19.
Sidaway, D.A. : A Microbiological Study of Dental Calculus. IV. An Electron Microscopic Study of in vitro Calcified Micro-organisms, J Periodont Res15 :240-254, 1980.
20.
Agus, H.M.; Schamschula, R.G.; Barmes, D.E.; and Bunzel, M.: Associations Between the Total Fluoride Content of Dental Plaque and Individual Caries Experience inAustralian Children, Community Dent Oral Epidemiol4 :210-214,1976.
21.
Rugg-Gunn, A.J.; Edgar, W.M.; Cockburn , M.A.; and Jenkins, G.N.: Correlations Between Fluoride Concentration, Sample Weight and Acid Production in Dental Plaque from Children, Arch Oral Biol26:61-63, 1981.
22.
Muhlemann, H.R.: Hydroxamates and Inhibition of Ureases - A Literature Review, Helv Odont Acta15(Suppl. VII) : 147-150,1971.
23.
Holloway, P.J. and Levine, R.S.: The Value of Self-applied Fluorides at Home, Int Dent J31:232-239, 1981.