Autoradiographs of molar teeth from 15-day-old rats that had been injected with 18F showed no tracer uptake in the late-mineralizing enamel. Autoradiographic and quantitative in vitro experiments indicated that the enamel organ limited fluoride uptake during the maturation phase of enamel formation.
Get full access to this article
View all access options for this article.
References
1.
Marthaler, T.M. : Fluoride Supplements for Systemic Effects in Caries Prevention. In: Continuing Evaluation of the Use of Fluorides, Johansen, E.; Taves, D.R.; and Olsen, T.O., Eds., Boulder, CO: Westview Press, 1979, pp. 33-37.
2.
Deutsch, D.; Weatherell, J.A.; and Hallsworth, A.S. : Uptake and Distribution of Fluoride in Developing Enamel, J Dent Res51:1278, 1972.
3.
Weatherell, J.A.; Deutsch, D.; and Hallsworth , A.S.: Fluoride Concentrations in Developing Enamel, Nature256:230-232, 1975.
4.
Ahlberg, M.; Bawden, J.W.; Hammarstrom, L.E.; and Hellborg, R.: Proton Activation Analysis Studies on Fluorine and Nitrogen Content of Developing Enamel, Odont Revy26:267-280, 1975.
5.
Weatherell, J.A.; Deutsch, D.; Robinson , C.; and Hallsworth , A.S.: Assimilation of Fluoride by Enamel Throughout the Life of the Tooth, Caries Res (Suppl.)11 :85-115,1977.
6.
Speirs, R.L. : Fluoride Incorporation into Developing Enamel of Permanent Teeth in the Domestic Pig, Arch Oral Biol20: 877-883, 1975.
7.
Speirs, R.L. : Incorporation of a Dietary Fluoride Supplement into Bone and Developing Teeth of the Domestic Pig, Arch Oral Biol23:1013-1017, 1978.
8.
Speirs, R.L. : Retention of Fluoride by Enamel During Maturation in Unerupted Permanent Teeth of the Domestic Pig,Arch Oral Biol25:805-808, 1980.
9.
Deutsch, D. (Personal communication).
10.
Hammarström, L.: Distribution in Developing Rat Enamel of Simultaneously Injected Fluoride and Calcium, Scand J Dent Res79:369-376, 1971.
11.
Whitford, G.M. and Lake, F.T.: Distribution of 18F in Unerupted Rat Incisor Enamel, IADR Progr & Abst58: No. 231,1979.
12.
Ullberg, S.: Studies on the Distribution and Fate of 35S Labeled Benzylpenicillin in the Body, Acta Radiol Suppl. 118:22-31, 1954.
13.
Bawden, J.W. and Wennberg A.: In vitro Study of Cellular Influence on 45Ca Uptake in Developing Rat Enamel , J Dent Res56:313-319,1977.
14.
Crenshaw, M.A. ; Wennberg, A.; and Bawden, J.W.: Fluoride-binding by the Organic Matrix of Developing Bovine Enamel, Arch Oral Biol23:285-287, 1978.
15.
Crenshaw, M.A. and Bawden, J.W.: Fluoride-binding by Organic Matrix from Early and Late Developing Bovine Fetal Enamel Determined by Flow-rate Dialysis , Arch Oral Biol, In press.
16.
Petersson, L.G.; Odelius, H.; Lodding , A.; Larsson, S.J.; and Frostell , G.: Ion Probe Study of Fluoride Gradients in Outermost Layers of Human Enamel, J Dent Res55 :980-990,1976.
