The production of stimulated parotid saliva was examined in 208 adults, aged 23-88 yr. Among men and women, taking no prescription medication, there was no diminution of stimulated parotid fluid output with increased age. Of subjects taking medication, post-menopausal women (but not older men) produced stimulated saliva at rates significantly lower than their non-medicated counterparts.
Get full access to this article
View all access options for this article.
References
1.
Andrew, W.: A Comparison of Age Changes in Salivary Glands of Man and of the Rat , J Geront7:178-190, 1952.
2.
Bauer, W.H.: Old Age Changes in Human Parotid Glands with Special Reference to Peculiar Cells in Uncommon Salivary Gland Tumors, IADR Progr & Abst29: No. 686, 1950.
3.
Scott, J.: Degenerative Changes in the Histology of the Human Submandibular Salivary Gland Occurring with Age, J Biol Buccale5:311-319, 1977.
4.
Waterhouse, J.P.; Chisholm, D.M.; Winter, B.B.; Patel, M.; and Yale, R.S.: Replacement of Functional Parenchymal Cells by Fat and Connective Tissue in Human Submandibular Salivary Glands: An Age-related Change, J Oral Path2:16-27, 1973.
5.
Mason, D.K. and Chisholm, D.M.: Salivary Glands in Health and Disease, London : W. B. Saunders Co., 1975.
6.
Mandel, I.D. and Wotman, S.: The Salivary Secretions in Health and Disease , Oral Sci Rev8:25-47, 1976.
7.
Baum, B.J.: Salivary Glands and Saliva: Recent Advances in Understanding Their Function and Role in Oral Health, New Dentist9:21-26, 1979.
8.
Meyer, J. and Necheles, H.: Studies in Old Age. IV. The Clinical Significance of Salivary, Gastric, and Pancreatic Secretion in the Aged, J Am Med Assoc115:2050-2053, 1940.
9.
Becks, H. and Wainright, W.W.: Human Saliva. XIII. Rate of Flow of Resting Saliva of Healthy Individuals , J Dent Res22 :391-396,1943.
10.
Bertram, U. : Xerostomia, Acta Odont Scand25: Supplement49, 1967.
Brun, R. and Domine, E.: Etude sur la transpiration, Acta Dermato-Venereo38 :91-103,1958.
13.
Baum, B.J.: Current Research on Aging and Oral Health, Special Care Dent , In press.
14.
Davidoff, A.; Winkler, S.; and Lee, M.H.M.: Dentistry for the Special Patient: The Aged, Chronically III, and Handicapped , Philadelphia, PA: W.B. Saunders Co., 1972, pp. 51-52.
15.
Nizel, A.E. : Role of Nutrition in the Oral Health of the Aging Patient, Dent Clin North Am20:569-571, 1976.
16.
Langer, A.: Oral Signs of Aging and Their Clinical Significance, Geriatrics31:63-69, 1976.
17.
Storer, R.: The Oral Tissues. In: Textbook of Geriatric Medicine and Gerontology , Brocklehurst, J.C., Ed., London: Churchill Livingstone, 1978 , pp. 339-340.
18.
MacHudis, M.: Dentistry for the Elderly. In: Clinical Aspects of Aging, Reichel, W., Ed., Baltimore, MD: Williams and Wilkins Co., 1978, pp. 413-425.
19.
Stone, J.L. and Norris, A.H.: Activities and Attitudes of Participants in the Baltimore Longitudinal Study, J Geront21: 575-580,1966.
20.
Rowe, J.W.; Andres, R.; Tobin, J.W.; Norris, A.H.; and Shock, N.W.: The Effect of Age on Creatinine Clearance in Man: A Cross-sectional and Longitudinal Study, J Geront31:155-163, 1976.
21.
Carlson, A.V. and Crittenden, A.L.: The Relation of Ptyalin Concentration to the Diet and to the Rate of Secretion of the Saliva, Amer J Physiol26:169-177, 1910.
22.
Dawes, C.: The Effects of Flow Rate and Duration of Stimulation on the Concentrations of Protein and the Main Electrolytes in Human Parotid Saliva, Arch Oral Biol14: 277-294, 1969.
23.
Baum, B.J.: Aging and Oral Motor Function. In: Oral Motor Behavior: Impact on Oral Conditions and Dental Treatment, Bryant, P., Gale, E., and Rugh, J., Eds., Bethesda: NIH Publication No. 79-1845, 1979, pp. 244-252.