Synthetic culture medium containing potato starch and 1 gm% sucrose, with and without human parotid saliva, were pre-incubated. Filtrates from these mixtures were then incubated with Streptococcus mutans. S. mutans colonization on glass rods was suppressed in the cultures using filtrates from saliva and starch interaction. No inhibition was noted in filtrates pre-treated with parotid saliva in the absence of starch. The results suggest that the hydrolysis of starch by saliva yields by-products which inhibit in vitro S. mutans colonization.
Get full access to this article
View all access options for this article.
References
1.
Frostell, G. and Baer, P.N.: Effect of Sucrose, Starch and a Hydrogenated Starch Derivative on Dental Caries in the Rat, Acta Odont Scand29:253, 1971.
2.
Schafer, W.G.: The Caries-producing Capacity of Starch, Glucose, and Sucrose Diets in the Syrian Hamster, Science110: 143-144, 1949.
3.
Bernfeld, P.: Enzymes of Starch Degradation and Synthesis. In: Advances in Enzymology, Vol. XII, Nord, F. F., Ed., New York and London: Interscience Publishers, Inc., pp. 379-428, 1951.
4.
Knuuttila, M.L.E. and Makinen, K.K.: Effect of Maltose on Polysaccharide Synthesis by a Cariogenic Streptococcus, J Dent Res51:674, 1972.
5.
Balekjian, A.H. ; Longton, R.W.; Cole , J.S., III; and Guidry , M.S.: The Effect of Disaccharides on the Plaque-forming Potential of Streptococcus mutans, J Dent Res56: 1359-1363,1977.
6.
Gibbons, R.J. and Hygaard, M.: Synthesis of Insoluble Dextran and its Significance in the Formation of Gelatinous Deposits by Plaque-forming Streptococci, Arch Oral Biol13:1249-1262, 1968.
7.
Newbrun, E.; Finzen, F.; and Sharma, M.: Inhibition of Adherence of Streptococcus mutans to Glass Surfaces , Caries Res11 :153-159,1977.
8.
Carlsson, J. : Nutritional Requirements of Streptococcus mutans , Caries Res4 :305-320, 1970.
9.
Keene, H.J.: Parotid Fluid Collection System with Vacuum Trap Modification, J Dent Res42:1041, 1963.
10.
Balekjian, A.Y.; Cole, J.S., III; and Guidry , M.S.: Plaque Formation by Streptococcus mutans: An in vitro Method for Quantitative Determination , J Dent Res56: 696,1977.
11.
Newbrun, E. ; Prakabpol, A.; and Sharma, M.: Inhibitory Studies of Some Sugars and Dextrans on Glucosyltransferases, J Dent Res IADR Progr & Abst53:No. 477, 1974.
12.
Newbrun, E. ; Shulgin, A.; Abrams , B.; and Sharma, M.: Oligosaccharides Produced by Glycosyltransferase Action on Sucrose: Maltose Mixtures, J Dent Res54: L18, No. L72, 1975 .
13.
Birkhed, D. : On the Cleavage of Starch and Disaccharides in the Human Oral Cavity, Odont Revy25(31):5-35, 1974.
