The secretion of N-acetyl-β-glucosaminidase of mouse submaxillary gland into saliva was stimulated by norepinephrine and phenylephrine but not by pilocarpine and isoproterenol. The stimulative effects of the α-adrenergic agents were inhibited by α-blockers, phentolamine, and phenoxybenzamine. These results suggest that the secretion of the enzyme is regulated through α-adrenergic receptors.
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