The effect of autogenous marrow and calcitonin on reactions to a tricalcium phosphate ceramic was studied by subcutaneous implantation in rats. No bone formation was evident in association with uncoated and calcitonin-coated ceramic. At four weeks and thereafter bone formation was evident in association with all marrow-coated implants.
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References
1.
Duquette, P.: An evaluation of the osteogenic potential of a porous single-phase tricalcium phosphate ceramic. Thesis. Indiana UniversitySchool of Dentistry, 1973.
2.
Cushing, M.: Autogenous red marrow grafts and their potential for induction of osteogenesis . J Periodontol40:492-497, 1969.
3.
Mantzavinos, Z.; and Listgarten , M.A.: Thyrocalcitonin stimulated bone formation by local application to rat calvaria in vivo. J Periodontol41 :663-666,1970.
4.
Foster, S.C. ; and Kronman, J.H.: The effect of topical thyrocalcitonin on the extraction sites in the jaws of dogs. Oral Surg38:866-873, 1974.
5.
Shamash, D.B. ; and Bissada, N.F.: Stimulation of osteogenesis by topical application of calcitonin in periodontal osseous defects. J Periodontol48:619-629, 1977.
6.
Driskell, T.D.: Miter, Inc., Worthington, Ohio: Personal communication. February, 1978.
7.
Burwell, R.G. : Studies in the transplantation of bone. VII. The fresh composite homograft-autograft of cancellous bone. An analysis of factors leading to osteogenesis in marrow transplants and in marrow containing bone grafts. J Bone Joint Surg46-B: 110-140, 1964.
8.
Cutright, D.E. ; Bhaskar, S.N.; Brady, J.M.; Getter, L.; and Posey, W.R.: Reaction of bone to tricalcium phosphate ceramic pellets. Oral Surg33 :850-856, 1972.
9.
McDavid, P.T. ; El-Kafrawy, A.H.; and Mitchell , D.F.: Lack of effect of topical calcitonin on connective tissue. J Dent Res56:540, 1977.
10.
Newman, M.G. ; and Boyne, P.J.: Effect of calcified bone matrix on the osteogenic potential of hemopoietic marrow. Oral Surg32:506-512,1971.