Tooth transplants should not preclude future transplants in the recipient. In this study teeth failed to stimulate immunologic memory in weakly disparate mice. The teeth did carry transplantation antigens and were rejected after second-set skin grafts. The teeth probably enhanced their own survival through some immunoregulatory mechanism.
Get full access to this article
View all access options for this article.
References
1.
Shulman, L.B.: The Current Status of Allogenetic Tooth Transplantation. CIBA FOUNDATION Symposium II, Amsterdam, 1973.
2.
Ivanyi, D., and Kominek, J.: Tooth Allografts in Children Matched for HLA. Transplantation23:255-260,1977.
3.
Riviere, G.R.; Derkowski, J.L.; Neffe, J.R.: Cell-Mediated Lymphocytotoxic Response to Orthotopic Tooth Allografts by RHL-A-Matched Rhesus Monkeys, Transplantation23:176-197, 1977.
4.
Riviere, G.R. ; and Hildemann, W.H.: Orthotopic Transplantation of Tooth Buds Among Histoincompatible Mice, Transplantation16:655-663, 1971.
5.
Riviere, G.R. : Cytotoxic Antibodies and Lymphocytes Induced by Orthotopic Tooth Bud Allografts in Mice. J Immunology112: 776-782, 1973.
6.
Riviere, G.R. ; Sabet, T.Y.; Hoffman, R.L.: Transplantation of Tooth Buds Across a Multiple Non-H-2 Barrier, Transplantation12:271-278, 1971.
7.
Klein, J.: Tooth Transplantation in the Mouse: III. The Role of Minor (non-H-2) Histocompatibility Loci in Tooth Germ Transplantation, Transplantation12:500-508, 1971.
8.
Riviere, G.R. ; and Derkowski, J.L.: The Histologic Evaluation of Teeth Transplanted Between Weakly Disparate Genetically Defined Mice., Oral Surg, Oral Path, Oral Med, 42:582-587,1976.
9.
Billingham and Silvers (ed.): Transplantation of Tissues and Cells, The Wistar Institute Press, Philadelphia, 1961.
10.
Cantrell, J.L. , and Hildemann, W.H.: Characteristics of Disparate Histocompatibility Barriers in Congenic Strains of MiceI. Graft-Versus-Host Reactions, Transplantation14: 761-770,1972.
11.
Hildemann, W.H.; Morgan, M.; and Frautnick, L.: Immunogenetic Components of Weaker Histocompatibility Systems in Mice. Transplantation2:24-31, 1970.
12.
Hoffman, R.L. : Formation of Periodontal Tissues Around Subcutaneously Transplanted Hamster Molars, J Dent Res, 39:781-798, 1960.
13.
Sharav, Y.; Metzger, Z.; and Weinreb, M.M.: Behavior and Fate of Transplanted Tooth Buds: IV. Tolerance Induced by Tooth Buds Allografted Across the Major Histocompatibility System in Rats, Transplantation13:360-363,1972.
14.
Cantrell, J.L. , and Hildemann, W.H.: Characteristics of Disparate Histocompatibility Barriers in Congenic Strains of Mice: II. Antibody-Associated Suppression . J. Immunology, 110:629-636, 1973.
