Daily topical application of 2% NaF on hamster molars for 4 days in vivo, followed by acidulation (grapefruit beverage, pH 3.3) resulted in a lower caries rate than NaF followed by water application. Fluoride uptake was somewhat higher, but not significantly so in the acidulated group.
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References
1.
Brudevold, F. ; Aasenden, R.; Mccann, H.G. III; and Mccann , H.G.: Use of an Enamel Biopsy Method for Determination of In Vivo Uptake of Fluoride from Topical Treatments, Caries Res3: 119-133, 1969. 2. Gedalia, I.; Azriel, B.; Zalkind, M.; Eisdorfer, J.E.; and Segal, B.: Uptake of Topical Applied Fluoride in Enamel Pretreated with Phosphoric or Citric Acid, J Dent Res50: 1358, 1971.
2.
Depaola, P.F. ; Aasenden, R. ; and Brudevold , F.: The Use of Topically Applied Acidulated Phosphate-Fluoride Preceded by Mild Etching of the Enamel. A One Year Clinical Trial, Arch Oral Biol16 :1155-1163, 1971.
3.
Gedalia, I.; Anaise, J.; Westreich, V.; and Fuks, A.: Predisposition to Caries in
4.
Hamsters Following the Erosive Effect of a Commercial Citrus Beverage Administered With and Without Supplemental Fluoride, J Dent Res54:496-499, 1975.
5.
Kempler, D.; Anaise, J.; Westreich, V.; and Gedalia, I.: Caries Rate in Hamsters Given Nonacidulated and Acidulated Tea, J Dent Res56: 89, 1977.
6.
Hellstrom, I. , and Ericsson, Y.: Fluoride Reactions with Dental Enamel Following Different Forms of Fluoride Supply, Scand J Dent Res84: 255-267, 1976.
7.
Larsen, M.J. : In Vitro Studies of Fluoride Uptake in Human Enamel, Scand J Dent Res82:448-454, 1974.
8.
Keyes, P.H.: A Method of Recording and Scoring Gross Carious Lesions in the Molar Teeth of Syrian Hamsters, J Dent Res23: 439-444, 1944.
9.
Brudevold, F. ; Mccann, H.G.; Nilsson, R.; Richardson, B.; and Coklika, V.: The Chemistry of Caries Inhibition. Problems and Challenges in Topical Treatments, J Dent Res46:37-45, 1967.
10.
Graubart, J. ; Gedalia, I.; and Pisanti, S.: Effects of Fluoride Pretreatment In Vitro on Human Teeth Exposed to Citrus Juice, J Dent Res51:1677, 1972.
11.
Lehman, L.; Gedalia, I.; and Westreich, V.: Fluoride in Teeth of Rats Using Citrus Beverage, Ann Dent33:2-6, 1974.
12.
Kirkegaard, E. : Discussion to: Phys ;co-chemical Aspects of Fluoride-Apatite Systems Relevant ot the Study of Dental Caries, Caries Res11 (Suppl.) :167-170, 1977.
13.
Green, R.M. , and Hartles, R.L.: The Effects of Topically Applied Agents Containing Fluorides on Dental Caries in the Albino Rat, Arch Oral Biol11:727-736, 1966.
