The pH values of xylitol-containing plaque suspensions of persons who habitually used xylitol and sorbitol during 3.2 to 4.5 years did not significantly differ from those observed with suspensions containing no added carbohydrates. Sorbitol produced in 22-hour incubations pH values as low as 3.9 to 5.5. The activity of plaque xylitol dehydrogenase was almost nil, whereas sorbitol dehydrogenase activity was higher. The nonacidogenic nature of xylitol in relation to plaque did not change in prolonged use of xylitol.
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References
1.
Mäkinen, K.K. , and Scheinin, A.: Turku Sugar Studies. VII. Principal Biochemical Findings on Whole Saliva and Plaque, Acta Odontol Scand33 Suppl 70:129-171, 1975.
2.
Larmas, M.; Mäkinen, K.K.; and Scheinin, A.: Turku Sugar Studies. VIII. Principal Microbiological Findings, Acta Odontol Scand 33 Suppl70: 173-216, 1975.
3.
Gehring, F.; Mäkinen, K.K.; Larmas, M.; and Scheinin, A.: Turku Sugar Studies. X. Occurrence of Polysaccharide - Forming Streptococci and Ability of the Mixed Plaque Microbiota to Ferment Various Carbohydrates , Acta Odontol Scand 33 (Suppl70: 223-237, 1975.
4.
Larmas, M.; Scheinin, A.; Gehring, F.; and Mäkinen, K.K.: Turku Sugar Studies. XX. Microbiological Findings and Plaque Index Values in Relation to 1-Year Use of Xylitol Chewing Gum, Acta Odontol Scand 33 Suppl70:321-336, 1975.
5.
Gülzow, H.-J. : Comparative Biochemical Investigations on the Degradation of Sugars and Sugar Alcohols by Microorganisms of the Oral Cavity , Internat J Vit Nutr Res Suppl15:348-357, 1976.
6.
Mühlemann, H.R., and Deboever, J.: Radiotelemetry of the pH of Interdental Areas Exposed to Various Carbohydrates , in Dental Plaque, McHuGH, W.D. (ed), Dundee, Scotland: D.C. Thomson Co. Ltd, 1970, pp 179-186.
7.
Fitzgerald, R.J., and Keyes, P.H.: Demonstration of the Etiologic Role of Streptococci in Experimental Caries in the Hamster, JADA61:9-19, 1960.
8.
Edwardsson, S.: Characteristics of Caries-Inducing Human Streptococci Resembling Streptococcus mutans, Arch Oral Biol13: 637-646, 1968.
9.
Guggenheim, B.: Streptococci of Dental Plaques, Caries Res2:147-163, 1968.
10.
Noguchi, T. , and Mühlemann, H.R.: The Effect of Some Carbohydrates on In Vitro Growth of Streptococcus mutans and Actinomyces viscosus, Schweiz Mschr Zahnheilk86:1361-1370, 1976 .
11.
Mäkinen, K.K. : Microbial Growth and Metabolism in Plaque in the Presence of Sugar Alcohols, Sp Supp Microbiology Abstracts11:521-538, 1976.
12.
Mäkinen, K.K. : Biochemical Principles of the Use of Xylitol in Medicine and Nutrition with Special Consideration of Dental Aspects, Experientia4 Suppl. 30:8, 1977.
13.
Mäkinen, K.K. , and Scheinin, A.: Turku Sugar Studies. VI. The Administration of the Trial and the Control of the Dietary Regimen, Acta Odontol Scand33 Suppl 70 : 105-127, 1975.
14.
Mäkinen, K.K. , and Rekola, M.: Xylitol Binding in Human Dental Plaque, J Dent Res55:900-904, 1976.
15.
Gerlach, U., and Hiby, W.: Sorbitol Dehydrogenase, in Methods in Enzymatic Analysis, Bergmeyer, H.U. (ed), New York: Academic Press, 1974, 2nd Edition, Vol. 2, 569-573.
16.
Mäkinen, K.K. ; Läikkö, I.; Rekola, M.; and Scheinin, A.: Biochemical Changes in Plaque and Whole Saliva in Relation to One-Month Consumption of Xylitol and Sorbitol Chewing Gums , to be published.
17.
Mäkinen, K.K. : Dental Aspects of the Consumption of Xylitol and Fructose Diets, Int Dent J26:14-28, 1976.
18.
Mäkinen, K.K. , and Scheinin, A.: The Effect of Various Sugars and Sugar Mixtures on the Activity and Formation of Enzymes of Dental Plaque and Oral Fluid, Acta Odontol Scand30:259-275, 1972.
