Ammoniacal silver stain showed that there was a decrease in nucleohistones in zinc-deficient rat buccal hyperplastic epithelaum as compared to control. Autoradiographic study showed that there was decreased incorporation of 3H-arginine and3 H-lysine in the hyperplastic epithelium.
Get full access to this article
View all access options for this article.
References
1.
Alvares, O.F. , and Meyer, J. : Regional Differences in Parakeratotic Response to Mild Zinc Deficiency, Arch Dermatol98:191-201, 1968.
2.
Osmanski, C.P. , and Meyer, J.: Ultrastructural Changes in Buccal and Palatal Mucosa of Zinc-Deficient Rats, J Invest Dermatol53:14-28, 1969.
3.
Alvares, O.F. , and Meyer, J.: Thymidine Uptake and Cell Migration in Cheek Epithelium of Zinc-Deficient Rats, J Oral Pathol3:86-94, 1973.
4.
Meyer, J., and Alvares, O.F.: Dry Weight and Size of Cells in the Buccal Epithelium of Zinc-Deficient Rats: A Quantitative Study, Arch Oral Biol19:471-476, 1974.
5.
Stedman, E., and Stedman, E.: Cell Specificity of Histones, Nature (London)166:780-781, 1950.
6.
Georgiev, G.P. : Histones and the Control of Gene Action, Ann Rev Genet3:155-180, 1969.
7.
Macrae, E.K. , and Meetz, G.D.: Electron Microscopy of the Ammoniacal Silver Reaction for Histones in the Erythropoietic Cells of the Chick, J Cell Biol45:235-245, 1970.
8.
Black, M.M., and Ansley, H.R.: Histone Staining with Ammoniacal Silver, Science143:693-695, 1964.
9.
Prfscott, D.M. : The Synthesis of Total Macronuclear Protein, Histone and DNA during the Cell Cycle in Euplotes eurystomus, J Cell Biol31:1-9, 1966.
10.
Baserga, R. : Control of Cell Proliferation in Mammalian Cells: Role of Nuclear Acidic Proteins, J Invest Dermatol59:21-23, 1972.
11.
Gerner, E.W. , and Humphrey, R.M.: The Cell-Cycle Phase Synthesis of Non-histone proteins in Mammalian Cells, Biochim Biophys Acta331:117-127, 1973.
12.
Allfrey, V.G. ; Littau, V.C. ; and Mirsky, A.E.: On the Role of Histones in Regulating Ribonucleic Acid Synthesis in the Cell Nucleus, Proc Nat Acad Sci49:414-421, 1963.
13.
Bonner, J.F. and Tso, P.: The Nucleohistones, San Francisco, London, Amsterdam , Holden-Day, Inc., 1964.
14.
Busch, H.: Histones and Other Nuclear Proteins, New York and London, Academic Press, 1965.
15.
Johnmann, C. ; Eckhardt, R.A.; and Gorovsky , M.A.: The Histones Associated with Condensed and Extended Chromatin of Mouse Liver, J Cell Biol58:119-125, 1973.
16.
Hjelm, R.P. , Jr., and Huang, R.C.C.: The Role of Histones in the Conformation of DNA in Chromatin as Studied by Circular Dichroism, Biochemistry13:5275-5283, 1974.
17.
Vallee, B.L. : Biochemistry, Physiology and Pathology of Zinc , Physiol Rev39:443-490, 1959.
18.
Dunn, M.F., and Hutchison, J.S.: Roles of Zinc Ion and Reduced Coenzyme in the Formation of a Transient Chemical Intermediate During the Equine Liver Alcohol Dehydrogenase Catalyzed Reduction of an Aromatic Aldehyde, Biochemistry12:4882-4992, 1973.