Human gingival fibroblasts cultivated on collagen-coated cover slips had collagen fibrils in deep folds of the cell membranes after one hour and fully interiorized fibrils by 24 hours. In 5-day sections, fibrils were within dense bodies, some containing multiple dense granules (40 to 50 nm) aligned along the surface of the interiorized collagen fibrils.
Get full access to this article
View all access options for this article.
References
1.
Rose, G.G., and Robfrtson, P.B.: Collagenolysis by Human Gingival Fibroblast Cell Lines, J Dent Res56:416-424, 1977.
2.
Ten Cate, A.R. : Morphological Studies of Fibrocytes in Connective Tissue Undergoing Rapid Remodeling, J Anat112:401-414, 1972.
3.
Beertsen, W. ; Everts, V.; and Van Den Hooff A. : Fine Structure of Fibroblasts in the Periodontal Ligament of the Rat Incisor and Their Possible Role in Tooth Eruption, Arch Oral Biol19:1087-1098, 1974.
4.
Deporter, D.A. , and Ten Cate, A.R.: Fine Structural Localization of Acid and Alkaline Phosphatase in Collagen-containing Vesicles of Fibroblasts , J Anat114:457-461, 1973.
5.
Listgarten, M.A.: Intracellular Collagen Fibrils in the Periodontal Ligament of the Mouse, Rat, Hamster, Guinea Pig and Rabbit, J Periodont Res8:335-342, 1973.
6.
Ten Gate, A.R. , and Deporter, D.A.: The Role of the Fibroblast in Collagen Turnover in the Functioning Periodontal Ligament of the Mouse, Arch Oral Biol19 :339-340, 1974.
7.
Garant, P.R. : An Electron Microscopic Study of the Periodontal Tissues of Germ-free Rats and Rats Mono-infected with Actinomyces Naeslundii , J Periodont Res Supplement 15, 1976.
8.
Ten Cate, A.R. ; Deporter, D.A.; and Freeman, E.: The Role of Fibroblasts in the Remodeling of Periodontal Ligament During Physiologic Tooth Movement, Am J Orthodont69:155-168, 1976.
9.
Ten Cate, A.R. , and Deporter, D.A.: The Degradative Role of the Fibroblast in the Remodelling and Turnover of Collagen in Soft Tissue, Anat Rec182:1-14, 1975.
10.
Eley, B.M., and Harrison, J.D.: Intracellular Collagen Fibrils in the Periodontal Ligament of Man , J Periodont Res10:168-170, 1975.
11.
Ten Cate, A.R. , and Syrbu, S.: A Relationship Between Alkaline Phosphatase Activity and the Phagocytosis and Degradation of Collagen by the Fibroblast , J Anat117: 351-359, 1974.
12.
Ten Cate, A.R. , and Freeman, E.: Collagen Remodelling by Fibroblasts in Wound Repair. Preliminary Observations, Anat Rec179:543-546, 1974.
13.
Yajima, T.: Ultrastructural and Cytochemical Studies on the Remodelling of the Tracheal Cartilage, Arch Histol Jap39 :79-97, 1976.
14.
Brinkley, B.R. ; Murphy, P.; and Rich-Ardson , L.C.: Procedure for Embedding In Situ Selected Cells Cultured In Vitro, J Cell Biol35:279-283. 1967.
15.
Perez-Tamayo, R.: Collagen Resorption in Carrageenin Granulomas. II. Ultrastructure of Collagen Resorption, Lab Invest22 :142-159, 1970.
