Restricted accessResearch articleFirst published online 1977-10
The Effects of Fluoride on the Percentage Bacterial Composition of Dental Plaque,on Caries Incidence,and on the In Vitro Growth of Streptococcus mutans,Actinomyces viscosus,and Actinobacillus sp
Administration of 250 μ g/ml NaF in drinking water to rats reduced both caries incidence (P < 0.001) and the percentage of S mutans (0.01 > P > 0.001) although the percentage of Actinobacillus sp. was increased (P < 0.001). An Actinobacillus sp. and S mutans FA1 both proliferated in NaF broth only if the NaF > 10 μ g/ml. which was associated with the inhibition of acid production.
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References
1.
Huxley, H.G. : The Mechanisms of Action of Fluoride in Reducing Dental Caries Susceptibility, N Z Dent J70:250-254, 1974.
2.
Clark, W.B.; and Kreitzman, S.N.: Fluoride Supplementation During Lactation: Caries Inhibition Without Reduction in Enamel Solubility, J Dent Res51 :1577-1580, 1972.
3.
Regolati, B. ; Schait, A.; Schmid , R.; and Mühlemann, H.R.: The Effect of Titanium, Aluminum and Fluoride on Rat Caries, Helv Odont Acta18:92-96, 1974.
4.
Clark, W.B. ; Kreitzman, S.N.; and Howell, A.T.: Increased Caries Incidence by Oral Inoculation of Carciogenic Bacteria in Rats After Dietary Fluoride, Arch Oral Biol18:1445-1450, 1973.
5.
Beighton, D. , and Colman, G.: A Medium for the Isolation of Actinomycetaceae from Human Dental Plaque, J Dent Res55: 875-878, 1976.
6.
Larson, R.H. ; Mellberg, J.R.; Englan-Der , H.R.; and Senning, R.S.: Relation of Ambient and Enamel Fluoride (F) to Rat Caries, IADR Program and Abstracts of Papers, No. 864, 1974.
7.
Beighton, D. : The Effects of Cadmium on the Normal Fissure Plaque Flora of Sprague-Dawley Rats, Arch Oral Biol, 22:99-102, 1977.
8.
König, K.G.; Marthler, T.M.; and Mühlemann, H.R.: Methodik der kurzfrisitig erzeugten Rattenkaries, Dtsch Zahn-, Mund-u . Kieferheilk, 29:99-127, 1958.
9.
Snedecor, G.W., and Cochran, W.G.: Statistical Methods, 6th Edition. Iowa State University Press, Ames, Iowa , U.S.A., 1972.
10.
Colman, G.; Beighton, D.; Chalk, A.J.; and Wake, S.: Cigarette Smoking and the Microbial Flora of the Mouth, Aust Dent J21:111-118, 1976.
11.
Meynell, G.G. , and Meynell, E.: Theory and Practice in Experimental Bacteriology , 2nd Edition, Cambridge University Press, England, 1970, p. 74.
12.
Bibby, B.G. , and Van Kesteren , M.: The Effect of Fluoride on Mouth Bacteria, J Dent Res19:391-402, 1940.
13.
Wright, D.E. , and Jenkins, G.N.: The Effect of Fluoride on the Acid Production of Saliva-Glucose Mixtures, Brit Dent J96: 30-33, 1954.
14.
Harrison, R.W. : Bacteriological Studies of Experimental Dental Caries in the Rat, J Infect Dis67:91-96, 1940.
15.
Macdonald, J.B.; Socransky, S.; and Sawyer, S.: A Survey of the Bacterial Flora of the Periodontium in the Rice Rat, Arch Oral Biol1:1-7, 1959.
16.
Huxley, H.G. : A Study of the Variability of Dental Plaque Microorganisms in Litter-mate Wistar Rats Retaining a Natural Oral Flora, Arch Oral Biol19:935-940, 1974.
17.
Van Houte, J.; Backer Dirks, O.; De Stoppelaar , J.D.; and Jansen, H.M.: Iodophilic Polysaccharide-Producing Bacteria and Dental Caries in Children Consuming Fluoridated and Nonfluoridated Drinking Water, Caries Res3:178-189, 1969.
18.
Edgar, W.H. ; Jexkins, G.N.; and Tate-Vossian , A.: The Inhibitory Action of Fluoride on Plaque Bacteria. Further Evidence, Brit Dent J128:129-132, 1970.
19.
Geddes, D.A.M. , and Jenkins, G.N.: Factors Influencing the Mouth Flora, in The Normal Microbial Flora of Man, Soc Appl Bact Symp Ser No. 3. Skinner, F.A. and Carr, J.G. (eds). Academic Press, London, 1974, pp. 85-100.
