Oral submucosal blood flow was measured at dental injection sites in anesthetized dogs and compared with subcutaneous blood flow. Blood flow was calculated from the measured half-time for clearance of radioactive xenon dissolved in saline. By this method, oral submucosal blood flow was much greater than subcutaneous blood flow and was comparable in magnitude to values reported for cerebral blood flow. Injection of a solution containing 1:100,000 epinephrine at the mandibular canal produce a delayed clearance of isotope which was three times as long as the clearance time for solutions without epinephrine.
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References
1.
Klingenstrom, P.; Nylen, B.; and Westmark, L.: A Clinical Comparison between Adrenaline and Octapressin as Vasconstrictors in Local Anesthesia, Acta Anaesth Scand11: 35-37, 1967.
2.
Goldman, R., and Evers, H.: Prilocaine-Felypressin, a New Combination for Dental Analgesia, Dent Practit Dent Rec19:225-231, 1969.
3.
Sejrsen, P.: Measurement of Cutaneous Blood Flow by Freely Diffusible Radioactive Isotopes : Methodological Studies on the Washout of Krypton 85 and Xenon 133 from the Cutaneous Tissue in Man, Danish Med Bull 18 Suppl . 3:9-39, 1971.
4.
Kety, S.S.: Measurement of Regional Circulation by the Local Clearance of Radioactive Sodium, Am Heart J38:321, 1949.
5.
Larsen, O.A. ; Lassen, N.A.; and Quaade, F.: Blood Flow through Human Adipose Tissue Determined with Radioactive Xenon, Acta Physiol Scand66:337-345, 1966.
6.
Roberts, C. (ed) : Blood Flow Measurement, Baltimore: The Williams and Wilkins Co., 1972.
7.
Lassen, N.: On the Theory of the Local Clearance Method for Measurement of Blood Flow Including a Discussion of its Application to Various Tissues, Acta Med Scand (Suppl.)472:136-145, 1967.
8.
Lassen, N.: Studies of Peripheral Circulation, In Radioisotopes in Medical Diagnosis, E.H. Belcher and H. Vetter (eds) : London : Butterworths, 1971.
9.
Sejrsen, P.; and Tonnesen, K.: Inert Gas Diffusion Method for Measurement of Blood Flow Using Saturation Techniques: Comparison with Directly Measured Blood Flow in Isolated Gastrocnemius Muscle of the Cat, Circ Res22:679-693, 1968.
10.
Sejrsen, P. : Blood Flow in Cutaneous Tissue in Man Studied by Washout of Radioactive Xenon, Circ Res25:215-229, 1969.
11.
Anderson, A.M. ; and Ladefoged, J.: Partition Coefficient of Xenon 133 Between Various Tissues and Blood In Vivo, Scand J Clin Lab Invest19:72-78, 1967.
12.
Nielsen, S.L. : Measurement of Blood Flow in Adipose Tissue from the Washout of Xenon 133 after Atraumatic Labelling, Acta Physiol Scand84:187-196, 1972.
