Chronic calcitonin (CT) deficiency was shown to have several effects on the incisors of young growing rats. The incisors had a significantly wider predentin layer, interglobular dentin, and frequent pulpal exposures at the incisal edge. It was concluded that CT plays a role in the normal calcification of dentin matrix.
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References
1.
Baume, L.J.; Becks, H.; and Evans, H.M.: Hormonal Control of Tooth Eruption. III. The Response of the Incisors of Hypophysectomized Rats to Growth Hormone, Thyroxine, or the Combination of Both, J Dent Res33:104, 1954.
2.
Billingham, R.E., and Silvers, W.K. (eds): Transportation of Tissue and Cells, Wistar Institute Press, Philadelphia, 1961, pp 39-48.
3.
Copp, D.H.: Endocrine Regulation of Calcium Metabolism, Ann Rev Physiol32 :61-86, 1970.
4.
Donaldson, H.H.: The Rat, Reference Tables and Data for the Albino Rat and the Norway Rat, Wistar Institute, Philadelphia1951 , p 39.
5.
Farris, E.J., and Griffith, J.Q.: The Rat in Laboratory Investigation, Hafner Publishing Company, New York, 1971, pp 150.
6.
Gindler, E.M. , and King, J.D.: Rapid Colorimetric Determination of Calcium in Biologic Fluids with Methylthymal Blue. Amer J Clin Path58:376-382, 1972.
7.
Hirsch, P.F. ; Gauthier, G.F.; and Munson, P.L.: The Hypocalcemic Principle and Recurrent Laryngeal Nerve Injury as Factors Affecting the Response to Parathyroidectomy in Rats, Endocrinol73:244-252, 1963.
8.
Kumar, M.A., and Sturtridge, W.C. : The Physiological Role of Calcitonin Deficiency in Rats. J Physiol233:33-43, 1973.
9.
Kumar. M.A.; Sturtridge, W.C.; Jowsey, W.C.; and Wase, A.W.: Chronic Calcitonin Deficiency, in Taylor, S. (ed) : Calcitonin, London, W. Heineman Medical Books Ltd., 1968, pp 332-328.
10.
Matrajt, H.; Bordier, P.; Tun-Chot, S.; Hisco, D.; Foster, G.U.; and Dotle, F.H.: Histological Bone Changes Produced by Calcitonin, in Taylor, S. (ed) : Calcitonin, London , W. Heinmann Medical Books, Ltd., 1968, pp 338-346.
11.
Merck Index, Merck and Company, Inc., Rahway , New Jersey, 8th ed., 1968, p 1052.
12.
Russell, P.S. , and Gittes, R.F.: Parathyroid Transplants in Rats, J Exp Med109: 571-588, 1959.
13.
Schour, I., and Steadman, S.R.: The Growth Pattern and Daily Rhythm of the Incisor of the Rat, Anat Rec63:325-335, 1935.
14.
Sturtridge, W.C., and Kumar, M.A.: Calcium Homeostasis in Chronic Thyrocalcitonin Deficiency, Endocrinol81:1297-1300, 1967 .
