The dissolution behavior of enamel and synthetic hydroxyapatite in acidic media possessing a high degree of partial saturation was found to be neither simple surface dissolution nor linear with time. Instead, a repetitive, stepwise dissolution pattern was observed. To explain this phenomenon, a model based upon a hypothesis that the crystals dissolve in a synchronized fashion was proposed.
Get full access to this article
View all access options for this article.
References
1.
Higuchi, W.I. ; Gray, J.A. ; Hefferren, J.J.; and Patel, P.R.: Mechanisms of Enamel Dissolution in Acid Buffers, J Dent Res44: 330-341, 1965.
2.
Higuchi, W.I. ; Mir, N.A.; Patel , P.R.; Becker, J.W.; and Hefferren , J.J.: Quantitation of Enamel Demineralization Mechanisms : III. A Critical Examination of the Hydroxyapatite Model, J Dent Res48 :396-409, 1969.
3.
Mir, N.A. , and Higuchi, W.I.: The Mechanism of Action of Solution Fluoride upon the Demineralization Rate of Human Enamel, Arch Oral Biol14:901-920, 1969.
4.
Young, F.; Fawzi, M.B.; Dedhiya, M.G.; Wu, M.S.; and Higuchi, W.I.: Dual Mechanisms for Dental Enamel Dissolution in Acid Buffers, J Dent Res53 (Special Issue) : Abstract No. 57, 1974.
5.
Fox, J.L. ; Fawzi, M.B.; Higuchi , W.I.; Hefferren, J.J.; and Hwu, R.C.: A Two-Site Model for Enamel Dissolution in EDTA, J Dent Res53 (Special Issue) : Abstract No. 586, 1974.
6.
Higuchi, W.T., in Rowe, N.A. (ed): Dental Plaque: Interface, Ann Arbor, Mich: University of Michigan Press, 1973, pp 74-78.
7.
Wu, M.S. , and Higuchi, W.I.: Dissolution Rate Studies with Synthetic Hydroxyapatite Pellets in Acidic Buffers Employing the Rotating Disk Method , J Dent Res55 :496-505, 1976.
8.
Fawzi, M.B.; Young, F.; Higuchi, W.I.; and Hefferren, J.J.: Unusual Dissolution Behavior of Enamel in Partially Saturated Acidic Media , J Dent Res53 (Special Issue) : Abstract No. 868, 1974.
9.
Fox, J.L. ; Fawzi, M.B.; Wu , M.S.; and Higuchi, W.I.: A New Two-Site Model for Hydroxyapatite Dissolution Acidic Media, Arch Oral Biol, submitted for publication.
10.
Wu, M.S. ; Higuchi, W.I.; Dedhiya , M.G.; Shimabayashi , S.; and Hefferren, J.J.: Rotating Disk Method Studies of Dental Enamel and Synthetic Hydroxyapatite Dissolution , J Dent Res54 (Special Issue A) : Abstract No. L538, 1975.
11.
Moreno, E.C. ; Gregory, T.M.; and Brown, W.E.: Preparation and Solubility of Hydroxyapatite , J Research, NBS, 72A: 773, 1968.
12.
Fox, J.L. , and Higuchi, W.I.: Methodologies for Transport Calculations Involving Diffusion, Complex Chemical Equilibria, and Crystal Kinetics, J Dent Res, submitted for publication.
13.
Amin, K.N.: Solubility of Hydroxyapatite and Its Inhibition by Phosphate, Ph.D. thesis , University of Michigan, 1971 .
14.
Riddiford, A.C. : The Rotating Disk System, in Delahay, P. (ed) : Adaances in Electrochemistry and Electrochemical Engineering, Vol 4, New York: Interscience, 1966, p 47.
15.
Higuchi, W.I. ; Mir, N.A.; Parker , A.P.; and Hamlin, W.E.: Dissolution Kinetics of a Weak Acid, 1,1-Hexamethylene p-Tolysulfonylsemicarbazide, and Its Sodium Salt, J Pharm Sci54:8-11, 1965.
16.
Fawzi, M.B. ; Sonobe, T.; Higuchi , W.I.; and Hefferren , J.J.: Synchronized Crystal Dissolution Behavior for Tooth Enamel and Synthetic (NBS) HAP, J Dent Res56 :394-406, 1977.