Antibody Formation and Cell-Mediated Immunity to Dog Pulp Tissue Altered by N2 Paste via the Root Canal

Davis S.R. , Brayton S.M. , and Goldman M. : The morphology of the prepared root canal. A study utilizing injectable silicone. Oral Surg 34:642, 1972.

Brayton S.M. , Davis S.R. , and Goldman M. : Gutta percha root canal fillings. An in vitro analysis. Oral Surg 35:226, 1973.

Langeland K. : Root canal sealants and pastes, Dental Clinics of North America, 18:309, 1974.

Torneck C.D. : Reaction of rat connective tissue to polyethylene tube implants. Oral Surg 21: 379, 1966.

Kennedy D.R. , Hamilton T.R. , and Syverton J.T. : Effects on monkeys of introduction of hemolytic streptococci into root canals. J Dent Res 36: 494, 1957.

Rosengren L. : Inoculation of streptococcus mutans and other bacteria into dental pulps of rats. Isr J Dent Med 19: 1, 1970.

Rosengren L. : The antibody response to experimental streptococcal infection of the dental pulp of the cat. Odont Tskr 70: 261, 1962.

Barnes G.W. , and Langeland K. : Antibody formation in primates following introduction of antigens into the root canal. J Dent Res 45: 1111, 1966.

Okada H. , Aono M. , Yoshida M. , Munemotog K. , Nishida O. , and Yokomizo I. Experimental study on focal infection in rabbits by prolonged sensitization through dental pulp canals. Arch Oral Biol 12: 1017, 1967.

Honjo H. , Tsubakimoto K. , Utsumi N. , and Tsutsui N. : Localization of plasma proteins in the human dental pulp. J Dent Res 49: 888, 1970.

Naidorf I.J. : Immunoglubulins in periapical granulomas: A preliminary report. J Endod 1: 15, 1975.

Landsteiner K. , and Lample H. : Uberdie Einwirking van Formaldehyde aut Eiweissantigen 8. Mitteilung uber antigen. Z Immunol 26: 133, 1917.

Horsfall F.L. Jr. : Formaldehyde and serum protein, their immunologic characteristics. J Immunol 27: 553, 1934.

Jacobs J.L. , and Sommers S.C. : Specificity of formalized proteins. J Immunol 36: 531, 1939.

Yoshikawa S. : Studies on the vital reaction by haemolysin. II. Experiments by means of auto-antigen. Jap J Allergy, 13:1, 1964.

Nishida O. , Okada H. , Kawagoe K. , Tokunaga A. , Tanihata H. , Aono M. , and Yokomizo I. : Investigation homologons antibodies to an extract of rabbit dental pulp. Arch Oral Biol 16: 733, 1971.

Spector W.G. , Heesom N. , and Stevens J.E. : Factors influencing chronicity in inflammation of rat skin. J Path Bact 96: 203, 1968.

Ryan G.B. , and Spector W.G. : Natural Selection of long lived macrophages in experimental granulomata. J Pathol 99: 139, 1969.

Spector W.G. , and Heesom N. : The production of granulomata by antigen-antibody complexes. J Pathol 98: 31, 1969.

Spector W.G. , Reichold N. , and Ryan G.B. : Degradation of granulomata inducing microorganisms by macrophages. J Pathol 101: 339, 1970.

Eleazer P.D. , Farber P.A. , and Seltzer S. : Lack of lymphocyte stimulation by root canal products. J of Endodontics, 1:388, 1975.

Stavisky B.A. : Micromethods for the study of proteins and antibodies. I. Procedure and general applications of hemogglutination and hemogglutination-inhibition reaction with tannic acid and protein treated red blood cells. J Immunol 72: 360, 1954.

Thorsby E. , and Bartlin A. : A Rapid Method for Preparation of Pure Lymphocyte Suspensions, in Histocompatibility Testing, Baltimore, Md. Williams and Wilkins Co., 1970, p. 655, 656.

Byum A. : Separation of Leukocytes from Blood and Bone Marrow. Scand J Clin Lab Invest Vol. 21, Suppl. 97, 1968.

Bach M.L. , Solliday S. , and Stambuk M. : Detection of disparity in the mixed leukocyte culture test, in Histocompatibility Testing, Baltimore, Md. Williams and Wilkins Co., 1970, p. 643–653.

Guttuso J. : Histopathologic study of rat connective tissue responses to endodontic materials., Oral Surg 16: 713, 1963.

Rappaport H.M. : Haddonfield N.J. , Lilly G.L. , and Kapsilmalis P. : Toxicity of Endodontic Filling Materials., Oral Surg 18: 785, 1964.

Langeland K. , Guttuso J. , Langeland L.K. , and Tobon G. : Methods in the study of biologic responses to endodontic materials. Tissue response to N2. Oral Surg 27: 522, 1969.

Overdiek H.F. : Pulpenreaktion auf N2 in Jurzzeitversuch, Dent Zahnartzl Z, 10:786, 1960.

Keresztesi K. , and Kellner G. : Der Einfluss einiger zur orthograden Wurzel fulling gebrauchlicher Materialieu auF das Gewebe (Versuche an Zellkulturen), Osterr Z Stomatol, 61:412, 1964.

Feldmann G. , Nyborg H. , and Conrado C.A. : Tissue Reactions to Root Filling Materials III. A comparison between implants of root filling material N2 and silver in the jaws of rabbits., Odoniol Revy 18: 387, 1967.

Friend L.A. , and Brown R.M. : Tissue reactions to some root filling materials, Brit Dental J, 125:291, 1968.

Snyder D.E. , Seltzer S. , and Moodnik R. : Effects of N2 in experimental endodontic therapy., Oral Surg 21: 635, 1966.

Kawahara H. , Yamagumi A. , and Nakamura M. : Biologic testing of dental materials by means of tissue culture, Int Dental J, 18:443, 1968.

Spangberg L. : Biologic effects of root canal filling materials. Z. Effect in vitro of water-soluble components of root canal filling material on Hela cells, Odontol Rev, 20:1, 1969.

Spangberg L. , and Langeland K. : Biologic effects of dental materials. 1. Toxicity of root canal filling materials on Hela cells in vitro. Oral Surg 35: 402, 1973.

Antrim D.D. : Evaluation of the cytoxicity of root canal sealing agents on tissue culture cells in vitro: Grossman's sealer, N2 (permanent), Rickert's sealer, and cavit. J of Endodontics, 2:111, 1976.

Zerosi C. , Baratieri A. , and Amici G. : Osservazioni istologiche sul comportamento dei tessuti periapicali dopo otturazione canalare con cemento N2, Russ Trim Odontoiat, 15:555, 1959.

Nicholls E. : Resorbable canal fillings, including N2, in Trans Third Int Conf Endodontics, L.I. Grossman (Ed.), Philadelphia, 1963, pp. 144–157.

Iten J. : Klinische and histologische Untersuchungen mit dem WurzelFuellMaterial N2, Inaugural-Dissertation, Arnaud Druck, Bernoch, Basel, 1958.

Langeland K. : Root canal sealants and pastes, Dental Clinics of North America, 18:309, 1974.

Langeland K. : Debate: Is N2 an acceptable method of treatment? In Transactions of the Fifth International Conference of Endodontics, L.I. Grossman (Ed.), Philadelphia, 1973, pp. 205–238.

Landsteiner K. : The specificity of serological reactions, Harvard Univ. Press, Cambridge, Mass., 1945: D. Pressman and A.L. Grossberg, The Structural Basis of Antibody Specificity, Benjamin, New York, 1968.

Landsteiner K. , and van der Scheen J. : On Cross Reactions of Immune Sera to Azo Proteins. J Exp Med 63: 325, 1936.

Landsteiner K. , and van der Scheer J. : On the influence of acid groups in the serological specificity of azo proteins, J Exp Med, 45:1045, 1927.

Karush F. : The interaction of purified antibody with optically isomeric haptens., J Am Chem Soc 78: 5519, 1956.

Karush F. : The interaction of purified anti-Blucite side antibody to haptens., J Am Chem Soc 79: 3380, 1957.

Eisen H.N. , and Siskind G.W. : Variation in affinities of antibodies during the immune response, Biochemistry, 3:996, 1964.

Unpublished data.

Sela M. : Antigenicity: Some molecular aspects., Science 166: 1365, 1969.

Claman H.N. , and Chaperon E.A. : Immunologic complementation between thymus and marrow cells — a model., Transplant Rev 1: 92, 1969.

Claman H.N. , Chaperon E.A. , and Triplett R.F. : Immuno competence of transferred thymus-marrow J Immunol 92:828, 1966.

Miller J.F.A.P. : Lymphocyte interactions in antibody responses, Int Rev Cytology, 33:77, 1972.

Miller J.F.A.P. , and Mitchell G.F. : Thymus and antigen-reactive cells, Transplant Rev, 1:3, 1969.

Mitchison N.A. , Rajewsky K. , and Taylor R.B. : In Developmental aspects of antibody formation and structure, Sterz J. (Ed.), Czech Acad Sci Prague, 1970, p. 547.

Mitchison N.A. , Rajewsky K. , and Taylor R.B. : In Developmental aspects of antibody formation and structure, Sterzl J. , and Richa I. (Eds.), Academic Press, New York, 1970, pp. 547.

Feldmann M. , and Basten A. : All Interactions in Immune Response in vitro. III Specific Collaboration J Exp Med 136:49, 1972.

Feldmann M. : Cell interactions in the immune response in vitro. V. Specific collaboration via complexes of antigen and thymus — derived cell immunoglobulin. J Exp Med, 136:737, 1972.

Feldmann M. , Cone R.E. , and Marchalonis J.J. : Cell interactions in immune response in vitro. VI. Mediated by T cell surface monomuric 18M. Cell Immununol 9: 1, 1973.

Raff M.C. : T and B Lymphocytes and Immune Responses, Nature, 242:19, 1973.

Mosier D.E. , and Coppelson L.W. : A three-cell interaction required for the induction of the primary immune response in vitro. Proc Natl Acad Sci USA 61: 542, 1968.

Rosenthal A.S. , and Shevach E.M. : Function of the macrophages in antigen recognition by guinea pig T lymphocytes. I. Requirement for histocompatibility macrophages and lymphocytes. J Exp Med 138:1194, 1973.

Shevach E.M. , and Rosenthal A.S. : Function of macrophages in antigen recognition by guinea pig lymphocytes. II. Role of the macrophage in the regulation of genetic control of the immune response, J Exp Med 138:1213, 1973.

Paul W.E. : Functional specificity of antigenbinding receptors of lymphocytes., Transplant Rev 5: 130, 1970.

Arzt A.H. : The Sargenti root canal method (Success speaks for itself) J of Conn St Dent Assoc 50:70, 1976.

Harndt R. , and Kaul A. : Untersuchungen uber den Verleibdes Bleies in WurzelkanalFullmaterial N2. Dtsch Zahnarztl Z, 28:580, 1973.

Spangberg L. , and Engstrom B. : Organsika KnicksilverForeningar ochbly i en rot-Fyllnihgspasta. Tandlartidningen, 63:339, 1971.

Oswald R.J. , and Cohn S.A. : Systemic distribution of lead from root canal fillings, J of Endodontics, 1:59, 1975.