Fifteen μCi of 3H-thymidine was injected into the amniotic cavity of fetal rats from day 15 to 19 postinsemination. Analysis of radioautographs from these rats did not show increased mesenchymal cell activity to be responsible for medial rotation of the palatal shelves. Variations in cell activity in the older fetuses were mainly due to developing bone and glands.
Get full access to this article
View all access options for this article.
References
1.
I. Peter, K.: Die Entwicklung des Saugetier Gaumens, Ergeb Anat Entw Gesch25 : 448-454, 1924.
2.
Lazarro, C.: Sul Meccanismo di Chiasma de Palato Secondario, Monit Zool Ital51 : 249-273, 1940.
3.
Larsson, K.S. ; Bostrom, H.; and Carlsöö, S.: Studies on the Closure of Secondary Palate: I. Autoradiographic Study in the Normal Mouse Embryo, Exp Cell Res16: 379-383, 1959.
4.
Walker, B.E. : Special Components of Embryonic Mesenchyme , Anat Rec136:298, 1960.
5.
Larsson, K.S. : Studies on the Closure of the Secondary Palate: III. Autoradiographic and Histochemical Studies in the Normal Mouse Embryo , Acta Morph Neerl Scand4: 349-367, 1962.
6.
Walker, B.E. , and Fraser, F.C.: Closure of the Secondary Palate in Three Strains of Mice, J Embryol Exp Morphol4: 176-189, 1956.
7.
Wragg, L.E.; Diewert, V.M.; and Klein, M.: Spatial Relations in the Oral Cavity and the Mechanisms of Secondary Palate Closure in the Rat, Arch Oral Biol17: 683-690, 1972.
8.
Orban, B.J.: Oral Histology and Embryology, 4th ed, St. Louis: C. V. Mosby, 1957, pp 23-24.
9.
Sicher, H., and Bhaskar, S.N.: Orban's Oral Histology and Embryology, 7th ed, St. Louis: C. V. Mosby, 1972, pp 6-12.
10.
Mott, W.J.; Toto, P.D.; and Hilgers, D.C.: Labelling Index and Cellular Density in Palatine Shelves of Cleft Palate in Mice, J Dent Res48: 263-265, 1969.
11.
Nanda, R.: The Normal Palate and Induced Cleft Palate in Rat Embryos, MD thesis, University of Nijmegen, The Netherlands, 1969, pp 18-93.
12.
Enesco, M., and Leblond, C.P.: Increase in Cell Number as a Factor in the Growth of the Organs and Tissues of the Young Male Rat, J Embryol Exp Morphol10: 530-562, 1962.