This study compared tumor induction time and the type of tumor formed in rat submandibular glands implanted with 9,10-dimethyl-1,2-benzanthracene (DMBA) to glands ligated before implantation of DMBA. Results showed no difference in tumor induction time or the type of tumor formed.
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References
1.
Cataldo, E., Shklar, G.; and Chauncey, A.: Experimental Salivary Gland Tumors in Rats, Arch Pathol77: 305-316, 1964.
2.
Bhaskar, S.; Bolden, T.; and Weinmann, J.P.: Experimental Obstructive Adenitis in the Mouse, J Dent Res35: 852-862, 1956.
3.
Standish, S.M. , and Shafer, W.G.: Serial Histologic Effects of Rat Submaxillary and Sublingual Gland Duct and Blood Vessel Ligation, J Dent Res36: 866-879, 1957.
4.
Standish, S.M. , and Shafer, W.G.: Experimental Carcinogenesis in the Duct-Ligated and Artery-Ligated Submaxillary Salivary Gland of the Rat, Am J Pathol36: 473-477, 1960.
5.
Cataldo, E., and Shklar, C.: Chemical Carcinogenesis in the Hamster Submaxillary Gland, J Dent Res43: 568-597, 1964.
6.
Ryser, H.J.-P: Chemical Carcinogenesis, N Engl J Med285: 721-734, 1971.
7.
Bryan, E.R., and Shimkin, M.B.: Quantitative Analysis of Dose-Response Data Obtained with Carcinogenesis Hydrocarbons , J Natl Cancer Inst1: 807-833, 1941.
8.
Schmutz, J.A. , and Chaudhry, A.P.: Incidence of Induced Tumors in the Rat Submandibular Gland with Different Doses of 7,12 Dimethylbenzaanthracene, J Dent Res48: 1316, 1969.
9.
Shklar, G.; Turbiner, S.; and Siegel, W.: Chemical Carcinogenesis of Hamster Mucosa Reaction to Dimethyl Sulfoxide, Arch Pathol87: 637, 1969.
10.
Berenblum, I.: Co-Carcinogenic Action of Croton Resin, Cancer Res1:44-48, 1941.
11.
Salomon, M.H. , and Rae, F.J.C.: Co-Carcinogenesis, Br Med Bull20: 139-144, 1964.
12.
Shklar, G., and Cataldo, E.: Effect of a Chemical Carcinogen on the Submaxillary Gland of Albino Rats Treated with Isoproterenol, Cancer Res26: 1319-1323, 1966.
13.
Law, L.W. : Studies of the Significance of Tumor Antigens in Induction and Repres sion of Neoplastic Diseases: Presidential Address , Cancer Res29: 1-21, 1969.
14.
Hellstrom, I.; Hellstrom, K.E.; Evans, C.A.; Heppner, G.H. ; Pierce, G.E.; and Yang, J.P.S.: Serum-Mediated Protection of Neoplastic Cells from Inhibition by Lymphocytes Immune to Their Tumor-Specific Antigens , Proc Natl Acad Sci USA62: 362-368, 1969.
15.
Macfarlane, G.: Immunological Factors in Carcinogenesis, Br Med Bull20: 154-157, 1964.
16.
Giunta, J.L. ; Reif, A.E.; and Shklar, G.: Bacillus Calmette-Guerin and Antilymphocyte Serum in Carcinogenesis, Arch Pathol98: 237-240, 1974.
17.
Shklar, G., and Turbiner, S.: Effect of Fluorouracil on Carcinogenesis of Rat Submandibular Glands, J Dent Res50: 985, 1971.
18.
Shklar, G.; Cataldo, E.; and Fitzgerald, A.: The Effect of Methotrexate on Chemical Carcinogenesis of Hamster Buccal Pouch , Cancer Res26: 2218-2223, 1966 .
19.
Mondal, S., and Heidelberger, C. : In Vitro Transformation by Methylcholanthrene of the Progeny of Single Cells Derived from C3H Mouse Prostate, Proc Natl Acad Sci USA65:4219-4225, 1970 .
20.
Hoffman, H.D. ; Lesko, S.A.; and Ts'o , P.: Chemical Linkage of Polycyclic Hydrocarbons to Deoxyribonucleic Acids and Polynucleotides in Aqueous Solution and in Buffer-Ethanol Solvent System, Biochemistry9: 2594-2603, 1970.
21.
Turbiner, S. ; Shklar, G.; and Cataldo, E.: The Effect of Cold Stress on Chemical Carcinogenesis of Rat Salivary Glands, Oral Surg29: 130-137, 1970.
22.
Junqueira, L.C.U.: Cytological, Cytochemical and Biochemical Observations on Secreting and Resting Salivary Glands, Exp Cell Res2: 327-338, 1951.
