Restricted accessResearch articleFirst published online 1975-09
Effects of Short-Term and Long-Term Administration of Procaine Hydrochloride and Mepivacaine Hydrochloride on Hexobarbital-Induced Sleeping Times in Mice
Investigations were performed to determine the effects of short-and long-term pretreatment with procaine and mepivacaine on hexobarbital-induced sleeping times in mice. It was found that short-term preadministration with procaine (40 mg/kg) and mepivacine (40 and 60 mg/kg) significantly increased hexobarbital-induced sleeping time, but long-term pretreatment had no effect.
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