GardnerA.F.; GrossS. G.; and WynneL.E.: An Investigation of Gingival Hyperplasia Resulting from Diphenylhydantoin Sodium Therapy in Seventy-seven Mentally-Retarded Patients, Exp Med Surg20: 133–158, 1962.
2.
AasE.: Hyperplasia Gingivae Diphenylhydantoinea, Boston: Scandinavian University Books, 1963, pp. 19–23.
3.
ConardG.J.: Pharmacological Aspects of Diphenylhydantoin Disposition, PhD thesis, University of Wisconsin, Madison, Wis, 1970, pp 34–49.
4.
ShaferW.O.: An Attempt to Produce Gingival Hyperplasia in the Albino Rat by the Administration of Dilantin Sodium, J Dent Res27: 768–769, 1948.
5.
SwensonH.M.: A Failure to Produce En-largement of Gingiva in Rats by Using Dilantin Sodium, J Dent Res33: 468, 1954.
6.
ConardG.J.; HaavikC.O.; and FingerK.F.: The Relationship of 5,5-Diphenyl-hydantoin Metabolism to the Species-Specific Induction of Gingival Hyperplasia in the Rat, Arch Oral Biol17: 311–321, 1972.
7.
NakamuraK., and MazudaY.: Effects of 5,5-diphenylhydantoin and 3-ethoxycarbonyl-5,5-diphenylhydantoin (P-6127) on the Dermal and Gingival Tissues of Experimental Animals, Arch Int Pharmacodyn Ther162: 255–264, 1966.
8.
EnneverJ.J., and PendoG.P.: Effect of Sodium Diphenyl Hydantoinate on the Gingiva of Swiss Mice, Wash Univ Dent J12: 70–73, 1946.
9.
StapleP.H.; HouckJ.C.; and NutterD.J.: Absence of Characteristic Reactions in the Periodontium and Other Peripheral Tissues of Hamsters Showing Neurophysiologic Response to Chronic Administration of 5,5-diphenylhydantoin (Dilantin), J Oral Ther Pharmacol3: 251–261, 1967.
10.
HorningM.G.; StrattonC.; WilsonA.; HorningE.C.; and HillR.M.: Detection of 5- (3,4-dihydroxy-1,5-cyclohexadien-1-yl) -5-phenylhydantoin as a Major Metabolite of 5,5-diphenylhydantoin (Dilantin) in the Newborn Human, Analytical Letters4: 537–545, 1971.
11.
ButlerT.C.: The Metabolic Conversion of 5,5-Diphenylhydantoin to 5- (p-hydroxypenyl) -5-phenylhydantoin, J Pharmacol Exp Ther119: 1–11, 1957.
12.
MaynertE.W.: The Metabolic Fate of Diphenylhydantoin in the Dog, Rat and Man, J Pharmacol Exp Ther130: 275–284, 1960.
13.
NoachE.L.; WoodburyD.M.; and Good-ManL.S.: Studies on the Absorption, Dis-tribution, Fate and Excretion of 4-C14-Labeled Diphenylhydantoin, J Pharmacol Exp Ther122: 301–314, 1958.
14.
ChangT.; SavoryA.; and GlazkoA.J.: A New Metabolite of 5,5-diphenylhydantoin (Dilantin®), Biochem Biophys Res Commun38: 444–449, 1970.
15.
GerberN.; WellerW.L.; LynnR.; RangnoR.E.; SweetmanB.J.; and BushM.T.: Study of Dose-Dependent Metabolism of 5,5-diphenylhydantoin in the Rat using New Methodology for Isolation and Quantitation of Metabolites In vivo and In vitro, J Pharmacol Exp Ther178: 567–579, 1971.
16.
ConardG.J.; HaavikC.O.; OsbornJ.C.; and HefferrenJ.J.: Simultaneous Gas-Liquid Chromatographic Determination of Diphenylhydantoin and Its Metabolites in Biological Specimens, abstracted, IADR Program and Abstracts of Papers, No. 515, 1972.
17.
HallW.B.: Dilantin Hyperplasia: A Pre-ventable Lesion, abstracted, IADR Program and Abstracts of Papers, No. 17, 1969.
18.
NukiK., and CooperS.: The Role of In-flammation in the Pathogenesis of Gingival Enlargement During the Administration of Diphenylhydantoin Sodium in Cats, J Periodont Res7: 102–110, 1972.
19.
KingJ.D., and GimsonA.P.: Experimental Investigations of Parodontal Disease in the Ferret and Related Lesions in Man, Br Dent J83: 148–149, 1947.
20.
KeyesP.H., and JordanH.V.: Periodontal Disease in the Syrian Hamster, III. Findings Related to an Infectious and Transmissible Component, Arch Oral Biol9: 377–400, 1964.
21.
NaviaJ.M.; LopezH.; and HarrisR.S.: Purified Diet for Dental Caries Research with Rats, J Nutr97: 133–140, 1969.
22.
LunaL.G.: Manual of Histologic Staining Methods of the Armed Forces Institute of Pathology, 3rd ed, New York: McGraw-Hill, 1968, p 34.
23.
ConardG.J.; JeffayH.; BoshesL.; and SteinbergA.D.: Levels of 5,5-Diphenyl-hydantoin and Its Major Metabolite in Human Serum, Saliva, and Hyperplastic Gingiva, J Dent Res53: 1323–1329, 1974.
