Drinking water of rats aged 21 days was supplemented with 1, 10, 30, 50, 100, or 283 ppm of boron or 10 or 25 ppm of fluoride individually or in combination. All rats were fed a cariogenic diet. Boron did not reduce dental caries activity in erupted molars after eight weeks. When given in combination, it partially antagonized the cariostatic effect of fluoride.
Get full access to this article
View all access options for this article.
References
1.
Curzon, M.E.J. ; Adkins, B.L.; Bibby, B.G.; and Losee, F.L.: Combined Effect of Trace Elements and Fluorine on Caries, J Dent Res49: 526-528, 1970.
2.
Losee, F.L., and Ludwig, T.G.: Trace Elements and Caries, J Dent Res49: 1229-1235, 1970.
3.
Losee, F.L., and Bibby, B.G.: Caries Inhibition by Trace Elements other than Fluorine, NY Dent J36: 15-19, 1970.
4.
Malthus, R.S. ; Ludwig, T.G.; and Healy, W.B.: Trace Elements and Dental Caries in Rats , J Dent Res44: 1207, 1965.
5.
Pappalardo, G.: Experimental Effects of Boron on Caries Prevention on the Albino Rats, Riv Ital Stomat5: 509-517, 1968.
6.
Kruger, B.J. : The Effect of Trace Elements on Experimental Dental Caries in the Albino Rat, University Queensland Papers , I: 1-28, 1959.
7.
Shaw, J.H., and Griffiths, D.: Developmental and Post-developmental Influences on Incidence of Experimental Dental Caries Resulting from Dietary Supplementation by Various Elements, Arch Oral Biol5: 301-322, 1961.
8.
Ludwig, T.G. ; Adkins, B.L.; and Losee, F.L.: Relationship of Concentrations of Eleven Elements in Public Water Supplies to Caries Prevalence in American School Children, Aust Dent J15: 126-132, 1970.
9.
Navia, J.M.: Prevention of Dental Caries: Agents which Increase Tooth Resistance to Dental Caries, Int Dent J22: 427-440, 1970.
10.
Hunt, C.E.; Navia, J.M.; Maxfield, L.M.; and Anderson, F.M.: Pre-eruptive Effects of Sr, Mo, Li, B and F on Dental Caries in the Rat, abstracted, IADR Program and Abstracts of Papers, No. 828, 1973.
11.
Hunt, C.E., and Navia, J.M.: Effects of Sr, Mo, Li, and B on Developing Teeth and other Tissues of Neonatal Rats, Conference on Trace Substances in Environmental Health-VI, 1973, pp 159-168.
12.
Liu, F.T.Y. , and Lin, H.S.: Effect of the Contraceptive Steroids Norethynodrel and Mestranol on Dental Caries Activity in Young Adult Female Rats, J Dent Res52: 753-757, 1973.
13.
Keyes, P.H. : Dental Caries in the Molar Teeth of Rats. II. A Method for Diagnosing and Scoring Several Types of Lesions Simultaneously J Dent Res37: 1088-1099, 1958.
14.
Larson, R.H. , Rubin, M.; and Zipkin, I.: Frequency of Eating as a Factor in Experimental Dental Caries, Arch Oral Biol7: 463-468, 1962.
15.
Hodge, H.C., and Smith, F.A.: Minerals: Fluoride and Dental Caries, in Harris, R.S.: (ed) : Dietary Chemical vs Dental Caries, Advances in Chemistry Series 94, Washington, DC: American Chemical Society, 1970.
16.
Brudevold, F.; Bakhos, Y.; and Gron, P.: Fluoride in Human Saliva After Ingestion of Aluminum Chloride and Sodium Fluoride or Sodium Monofluorophosphate, Arch Oral Biol18: 699-706, 1973.
