A study on various regimens by which the same total amount of neutral sodium fluoride is applied to the teeth of rats showed that greater effects were observed after frequent application of 0.2% solutions than after less frequent application of more concentrated solutions.
Get full access to this article
View all access options for this article.
References
1.
Sognnaes, R.F. : Effect of Topical Fluorine Application on Experimental Rat Caries, Br Dent J70: 433-437, 1941.
2.
König, K.G., and Muhlemann, H.R.: Caries Inhibiting Effect of Amine Fluoride Containing Dentifrices Tested in an Animal Experiment and in a Clinical Study, In Muhlemann, H.R., and Konig, K.G. (eds) : Caries Symposium, Zurich : The Present Status of Caries Prevention by Fluoride-Containing Dentifrices, Berne: Hans Huber, 1961, pp 126-132.
3.
König, K.G.; Green, R.M.; Schmid, R.; and Muhlemann, H.R.: The Effect of Mechanical Cleansing with Water or Dentifrices in a Rat Caries Study, Helv Odontol Acta8: 136-141, 1964.
4.
Green, R.M., and Hartles, R.M.: The Effect of Topically Applied Agents Containing Fluorides on Dental Caries in the Albino Rat, Arch Oral Biol11 :727-736, 1966.
5.
Green, R.M., and Hartles, R.L.: A Study on the Effects of Topical Application of Solutions and Dentifrices on the Incidence of Caries and the Surface Solubility of the Molar Teeth of the Albino Rat, Arch Oral Biol13: 115-124, 1968.
6.
Orbell, G.M.; McHugh, W.D.; and Fenton, P.: The Effect on Rat Caries of Topical Applications of TiF4 and Acid Fluoride Phosphate Solutions, J Dent Res53 (Special Issue), No. 685, 1973.
7.
Keyes, P.H., and Jordan, H.V.: Periodontal Lesions in the Syrian Hamster: III. Findings Related to an Infectious and Transmissible Component, Arch Oral Biol9: 377-400, 1964.
8.
Keyes, P.H.: Dental Caries in the Molar Teeth of Rats: II. A Method for Diagnosing and Scoring Several Types of Lesions Simultaneously, J Dent Res37: 1088-1099, 1958.
