Dissolution rates and apparent solubilities for synthetic hydroxyapatite in acetate buffers containing phosphate and strontium ions in the range of 10-3 to 10-2 M were determined under various pH and buffer conditions. Critical examination of the role of strontium with a physical model suggests that a calcium-strontium apatite surface complex may govern the driving force of the dissolution reaction.
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References
1.
Losee, F.L., and Bibby, B.G.: Caries Inhibition by Trace Elements Other Than Fluorine, NY State Dent J36: 15-19, 1970.
2.
Curzon, M.E.J. ; Adkins, B.L.; Bibby , B.G.; and Losee, F.L.: Combined Effect of Trace Elements and Fluorine on Caries, J Dent Res49: 526-528, 1970.
3.
Losee, F.L., and Ludwig, T.G.: Trace Elements and Caries, J Dent Res49: 1229-1235, 1970.
4.
Buonocore, M.G. , and Bibby, B.G.: The Effects of Various Ions on Enamel Solubilities , J Dent Res24: 103-108, 1945.
5.
Higuchi, W.I. ; Gray, J.A.; Hefferren , J.J.; and Patel, P.R.: Mechanism of Enamel Dissolution in Acid Buffers, J Dent Res44: 330-341, 1965.
6.
Higuchi, W.I. ; Mir, N.A.; Patel , P.R.; Becker, J.W.; and Hefferren , J.J. : Quantitation of Enamel Demineralization Mechanisms : III. A Critical Examination of Hydroxyapatite Model, J Dent Res48 : 396-409, 1969.
7.
Liang, Z.: Kinetics and Mechanism of Fluoride Uptake by Hydroxyapatite, PhD thesis, appendix IV, University of Michigan, 1971.
8.
Tennessee Valley Authority: Report No: 678, Alabama: Wilson Dam, Nov 6, 1956 .
9.
Dickman, S.R. , and Bray, R.H.: Calorimetric Determination of Phosphate , Ind Eng Chem12: 665-668, 1940.
10.
Neuman, W.F. ; Bjornerstedt, R.; and Mul-Ryan, B.J.: Synthetic Hydroxyapatite Crystals. II. Aging and Strontium Incorporation, Arch Biochem Biophys101:215-224, 1963.
11.
Likins, R.C. ; Mccann, H.G.; Posner , A.S.; and Scott, D.B.: Comparative Fixation of Calcium and Strontium by Synthetic Hydroxyapatite, J Biol Chem235: 2152-2156, 1960.
12.
Sakeb, F.Z. , and Debruyn, P.L.: Surface Properties of Alkaline Earth Apatite , J Electroanal Chem37:99-118, 1972.
13.
Nancollas, A.N.: Thermodynamics of Ion Association. Part II. Alkaline-Earth Acetates and Formates, J Phys Chem60 : 744-749, 1956.
14.
Sillen, L.G. , and Martell, A.E.: Stability Constants of Metal Ion Complexes, Special Publication No. 25, London: The Chemical Society, Burlington House, 1964.
15.
Mir, N.A. ; Higuchi, W.I.; and Hefferren , J.J.: The Mechanism of Action of Solution Fluoride Upon the Demineralization Rate of Human Enamel , Arch Oral Biol14 : 901-920, 1969.
16.
Brown, W.E. : Behavior of Slightly Soluble Calcium Phosphates as Revealed by Phase Equilibrium Calculations, Soil Sci90: 51-58, 1960.
17.
Hodes, B., and Higuchi, W.I.: Dissolution Rate Studies of CaHPO4·2H2O Employing the Rotating Disk Method, abstracted, IADR Program and Abstracts of Papers, No. 186, 1970.
18.
Hodes, B.: Dissolution Rate Studies of Some Calcium Phosphates Using the Rotating Disk Method, PhD thesis, University of Michigan, 1971.
19.
Hodes, B., and Higuchi, W.I.: Dissolution Rate Studies with Synthetic Hydroxyapatite, abstracted , IADR Program and Abstracts of Papers No. 473, 1972.
