This is a study of marmoset gingival fibroblast cells cultured adjacent to one surface of dentin disks after the other surface was treated with various fluoride solutions. Results indicate that sodium fluoride, stannous fluoride, and acidulated phosphate-fluoride solutions are not cytotoxic at clinically accepted concentrations and treatment exposure times.
Get full access to this article
View all access options for this article.
References
1.
Morch, T.; Selvig, K.A.; and Sand, H.F.: The Effect of Topically Applied Fluorides on the Acid Resistance of Human Dentin Studied by Means of P32 Uptake, Odontol Forem Tidskr76:163-170, 1968.
2.
Selvig, K.A. ; Sand, H.F.; and Morch, T.: The Effect of Topically Applied Fluorides on the Acid Resistance of Human Dentin Studied by Means of Microradiography , Odontol Forem Tidskr76:171-178, 1968.
3.
Andres, C.J. ; Stookey, G.K.; and Muhler, J.C.: Studies Concerning the Effect on the Dental Pulp in Dogs of a Stable Stannous Fluoride Solution Applied to Freshly Cut Dentin, J Oral Ther4:113-122, 1967.
4.
Massler, M., and Evans, J.A.: Pulpal Response to Stannous Fluoride Applied to Freshly Cut Dentin , J Dent Res46:1,469, 1967.
5.
Lefkowitz, W. , and Bodecker, F.F.: Sodium Fluoride: Its Effect on the Dental Pulp, Ann Dent3:141-146, 1945.
6.
Rovelstad, G.H. , and St. John , W.E.: The Condition of the Young Dental Pulp After the Application of Sodium Fluoride to Freshly Cut Dentin, JADA39:670-682, 1949.
7.
Perreault, J.G. ; Massler, M.; and Schour, I.: Reaction of Odontoblasts to Medicaments Placed in Cavity Preparations in Rat Incisors , JADA52:533-554, 1956.
8.
Maurice, C.G. , and Schour, I.: Effects of Sodium Fluoride Upon the Pulp of the Rat Molar, J Dent Res35:69-82, 1956.
9.
Rappaport, H.M. ; Lilly, G.E.; and Kap-Simalis , P.: Toxicity of Endodontic Filling Materials, Oral Surg18:785-801, 1964.
10.
Kawahara, H. ; Yamagami, A.; and Naka-Mura, M., JR.: Biological Testing of Dental Materials by Means of Tissue Culture, Int Dent J18:443-463, 1968.
11.
Gray, J.A., and Opdyke, D.L.: A Device for Thin Sectioning of Hard Tissues, J Dent Res41:172-181, 1962.
12.
Dulbecco, R. : Production of Plaques in Monolayer Tissue Culture by Single Particles of Animal Virus, Proc Natl Acad Sci USA38:747-755, 1952.
