Number and types of oral leukocytes counted in concatenated samples of saliva were related to the severity and extent of periodontal disease in 50 individuals between 19 and 65 years of age. The oral polymorphonuclear leukocyte level was independent of leukocyte levels in peripheral blood, and was correlated best with degrees of gingivitis.
Get full access to this article
View all access options for this article.
References
1.
KOLLIKER: cited in JASSINOWSKI, M.A.: Uber die Herkunft der Speichelkorperchen, Frankfurt Z Path31:411, 1925.
2.
Mendel, J.: Manner of the Phagocytic Reaction in the Oral Cavity of Man, C R Soc Biol70:925-928, 1916.
3.
Jassinowski M.: Uber die Herkunit der Speichelkorperchen , Frankfur Z Path31: 411, 1925.
4.
Retterei, E. , and Lelievre, A.: On the Nature and Origin of the Salivary Corpuscles, C R Soc Biol74:667-670, 1913.
5.
Gott, H.: Die Speichelkorperchen, Int Mschr Anat Physiol23:3-17, 1906.
6.
Sharry, J., and Krasse, B.: Observations on the Origin of Salivary Leukocytes, Acta Odontol Scand18:347-358, 1960.
7.
Klinkhamer, J.: Human Oral Leukocytes, Periodontics1:109-117, 1963.
8.
Skougaard, M. ; Bay, I.; and Klinkhamer , J.: Correlation between Gingivitis and Orogranulocytic Migratory Rate, J Dent Res48:716-718, 1969.
9.
Wright, D.E. : Leukocytes in the Saliva of Edentulous and Caries-Free Subjects, Arch Oral Biol7:381-385, 1962.
10.
Wright, D.: Leukocytes in the Saliva of Infants, Br Dent J110:50-53, 1961.
11.
Isaacs, R., and Danielian, E.: Maintenance of Leukocyte Level and Changes during Irradiation. A Study of the White Blood Corpuscles Appearing in the Saliva and Their Reaction to Those in the Blood. Am J Med Sci174:70-87, 1927.
12.
Allen, K., and Dickey, L.: The Saliva Cell Counts in Myelogenous Leukemia, Am J Roentgenol38:57-71, 1937.
13.
Watanabe, Y. : The Effect of Roentgen Irradiation upon the Cellular Elements in the Human Saliva, Oral Surg4:89-107, 1951.
14.
Comroe, B.: Salivary Changes in Systemic Disease, Dent Cosmos76:563-569, 1934.
15.
Stephens, D. , and Jones, E.: Leukocytes in the Saliva in Normal and Abnormal Subjects, Proc Soc Exp Biol Med31 :879-880, 1934.
16.
Orban, B., and Weinmann, J.: Cellular Elements of Saliva and Their Possible Role in Caries, J Dent Res18:258, 1939.
17.
Orban, B., and Weinmann, J.: Cellular Elements of Saliva and the Possible Role in Caries, JADA26:2008-2097, 1939.
18.
Calonius, P. : The Leukocyte Count in Saliva, Oral Surg11:43-46, 1958.
19.
Klinkhamer, J.: Quantitative Evaluation of Gingivitis and Periodontal Disease. I. The Orogranulocytic Migratory Rate, Periodontics6:207-211, 1968.
20.
Klinkhamer, J., and Zimmerman, S.: The Function and Reliability of the Orogranulocytic Migratory Rate as a Measure of Oral Health, J Dent Res48:709-715, 1969.
21.
Ramfjord, S. : The Periodontal Disease Index (P.D.I.), J Periodontol38:602-610, 1967.
22.
Greene, J.: The Oral Hygiene Index-Development and Uses, J Periodontol38: 625-635, 1967.
23.
Löe, H. , and Silvers, J.: Periodontal Disease in Pregnancy. II. Correlation between Oral Hygiene and Periodontal Condition, Acta Odontol Scand22:112-135, 1964.
24.
Davidsohn, I., and Henry, J.: Clinical Diagnosis by Laboratory Methods, 14th ed, Philadelphia: W. B. Saunders Co., 1969, pp 157-182.
25.
Dixon, W.J., and Massey, F.J.: Introduction to Statistical Analysis, New York : McGraw-Hill, 1969.
26.
Koch, G.G.: The Use of Non-Parametric Methods in the Statistical Analysis of a Complex Split Plot Experiment, Biometrics26:1, 1970.
27.
Davis, C.E. , and Quade, D.: On Comparing the Correlations Within Two Pairs of Variables, Biometrics24:987-995, 1968.
28.
Wright, D.: Differential Leukocyte Count of Human Saliva, Arch Oral Biol13 :1159-1161, 1968.
29.
Egelberg, J. , and Attstrom, R.: Presence of White Blood Cells within the Gingival Crevice, J Periodont Res4:161, 1969.
30.
Eichel, B., and Lisanti, V.: Leukocyte Metabolism in Human Saliva, Arch Oral Biol9:299-314, 1964.
31.
Dubos, R., and Hirsch, J.: Bacterial and Mycotic Infections of Man, 4th ed. Philadelphia : J. B. Lippincott Co. , 1965, pp 217-230.
32.
Florey, H.: General Pathology, 3d ed, Philadelphia: W. B. Saunders Co., 1962, pp 98-120.
33.
Goldman, H. , and Cohn, D.: Periodontal Therapy. St Louis: C. V. Mosby Co., 1968, pp 33, 126.
34.
Tempel, T.R. ; Snyderman, R.; Jordan , H.V.; and Mergenhagen , S.E. : Factors from Saliva and Oral Bacteria, Chemotactic for Polymorphonuclear Leukocytes: Their Possible Role in Gingival Inflammation , J Periodontol41:71-80, 1970.
35.
Attstrom, R. , and Egelberg, J.: Effect of Experimental Neutropenia on Gingival Inflammation in Dogs, J Periodont Res4: 24, 1969.
36.
Klinkhamer, J. : Personal communication.
37.
Löe, H. , and Holm-Pederson , P.: The Absence and Presence of Fluid from Normal and Inflamed Gingivae, Periodontics3:171-177, 1965.
38.
Mann, W.: The Correlation of Gingivitis, Pocket Depth and Exudate from the Gingival Crevice. J Periodontol34:379-387, 1963.
