Isobutyl cyanoacrylate produced varying degrees of growth inhibition when applied to freshly plated Petri dishes of Staphylococcus aureus, Gaffkya, Neisseria catarrhalis, and a-Streptococcus. A biproduct or diffusible substance produced by the polymer was implicated as the cause. Destruction of growing colonies was observed only with a-Streptococcus after polymer application. The mechanism for this was not determined.
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References
1.
Awe, W.C. ; Roberts, W.; and Brauwald, N.S.: Rapidly Polymerizing Hemostatic Agent: Study of Tissue Response and Bacteriological Properties, Surgery54:322, 1967.
2.
Bhaskar, S.N. ; Frisch, J.; Margetis, P.M.; and Leonard, F.: Application of a New Chemical Adhesive in Periodontic and Oral Surgery, Oral Surg22:526-535, 1966.
3.
Lehman, A.W.R. ; West, L.R.; and Leonard, F.: Toxicity of Alkyl 2-cyanoacrylate II Bacteria Growth, Arch Surg93:447-450, 1966.