Representative enzymes from four enzyme groups, which have been related to premalignant or malignant activity, were studied histochemically. Tissues from patients with papillary hyperplasia, normal denture-wearing patients, and normal non-denture-wearing patients were examined. No differences were noted in the distribution of the enzymes in the different tissues that could be related to premalignant or malignant change.
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References
1.
Shnitka, T.K. , and Seligman, A.M.: Role of Esteratic Inhibition on Localization of Esterase and the Simultaneous Cytochemical Demonstration of Inhibitor Sensitive and Resistant Enzyme Species, J Histochem Cytochem9:504-527, 1961.
2.
Burstone, M.S. : Histochemical Comparison of Naphthol AS-Phosphates for the Demonstration of Phosphatases, J Nat Cancer Inst20:601-613, 1958.
3.
Barka, T.: Cited by Hunt, R.D. in Thompson, S.W.: Selected Histochemical and Histopathological Methods, Spring-field, III: Charles C Thomas, 1966, pp 635-638.
4.
Barka, T.: A Simple Azo-Dye Method for Histochemical Demonstration of Acid Phosphatase , Nature187:248-249, 1960.
5.
Nachlas, M.M. ; Crawford, D.T.; and Seligman , A.M.: The Histochemical Demonstration of Leucine Aminopeptidase, J Histochem Cytochem5:264-278, 1957.
6.
Nachlas, M.M. ; Tsou, K.C.; Desouza , E.; Cheng, C.S.; and Seligman , A.M.: Cytochemical Demonstration of Succinic Dehydrogenase by the Use of a New p-Nitrophenyl Substituted Ditetrazole , J Histochem Cytochem5:420-436, 1957.
7.
Nachlas, M.M. ; Walker, D.G.; and Seligman , A.M.: A Histochemical Method of the Demonstration of Diphosphopyridine Nucleotide Diaphorase, J Biophys Biochem Cytol4:29-38, 1958.
8.
Kawakatsu, K. , and Mori, M.: Histochemical Evaluation of Enzymatic Activities in Human Squamous-Cell Cancer, Cancer Res23:539-545, 1963.
9.
Burstone, M.S. : Application of Histochemical Methods to Oral Pathology, Oral Surg10:296-303, 1957.
10.
Santis, H.; Shklar, G.; and Chauncey, H.H.: Histochemistry of Experimentally Induced Leukoplakia and Carcinoma of the Hamster Buccal Pouch, Oral Surg17: 207-218, 1964.
11.
Kawakatsu, K.; Mori, M.; and Naga-Suna, H.: Histochemical Study of Hydrolytic Enzymes and Dehydrogenases in Invading Carcinoma of Oral Mucosae, J Osaka Univ Dent Sch3:21-30, 1963.
12.
Burstone, M.S. : Histochemical Demonstration of Proteolytic Activity in Human Neoplasms, J Nat Cancer Inst16:1149-1161, 1956.
13.
Glenner, G.G. ; Burstone, M.S.; and Meyer, D.B.: A Study of Aminopeptidase Activity in the Stroma of Neoplastic Tissue, With a Comparison of Histochemical Techniques , J Nat Cancer Inst23:857-873, 1959.
14.
Okamoto, Y. ; Oka, R.; and Mort, M.: Histochemical Study of Aminopeptidase in Tumors of the Oral Region, Oral Surg16:733-737, 1963.
15.
Mori, M., and Kishiro, A.: Histochemical Observation of Aminopeptidase Activity in the Normal and Inflamed Oral Epithelium, J Osaka Univ Dent Sch1: 39-45, 1961.
16.
Mori, M.; Mizushima, T.; Oka, R.; Okamoto, Y.; and Takita, Y.: Histochemical Observations of Succinic, Malic, and Lactic Dehydrogenase in Oral Tumors, Oral Surg17:352-363, 1964.
Shklar, G.: The Precancerous Oral Lesion, Oral Surg20:58-70, 1965.
19.
Bhaskar, S.N. ; Beasley, J.D., III; and Cutright , D.E.: Inflammatory Papillary Hyperplasia of the Oral Mucosa: Report of 341 Cases, JADA81:949-952, 1970.
20.
Flanagan, V.D. , and Porter, K.: Histochemical Studies on Papillary Hyperplasia of the Palate. I. Metachromasia, Mast Cells, Acid Mucopolysaccharides, and Glycogen, Oral Surg26:660-666, 1968.