Thyrotoxic rats developed severe periodontal disease after a few weeks on a purified diet containing all known nutrients. Lesions did not occur in thyrotoxic rats fed a natural food stock ration nor the purified diet with dietary supplements.
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References
1.
Wilson, R.H. , and Deeds, F.: Importance of Diet in Studies of Chronic Toxicity, Arch Ind Hyg Occup Med1:73-80, 1950.
2.
Woolley, D.W., and Kramprrz , L.O.: Production of a Scurvy-Like Condition by Feeding of a Compound Structurally Related to Ascorbic Acid, J Exp Med78: 333-339, 1943.
3.
Ershoff, B.H. : Comparative Effects of a Purified and Stock Diet on DBH (2,5,-Di-Tert-Butylhydroquinone) Toxicity in the Rat, Proc Soc Exp Biol Med112:362-365, 1963.
4.
Ershoff, B.H. : Nutrition and Stress, Nutr Rev13:33-36, 1955.
5.
Ershoff, B.H. : Unidentified Nutritional Factors and Resistance to Stress, J Dent Med16:71-76, 1961.
6.
Miller, E.D. ; Miller, J.A.; Sandin , R.B.; and Brown, R.K.: The Carcinogenic Activities of Certain Analogues of 2-Acetylaminofluorene in the Rat, Cancer Res9: 504-509, 1949.
7.
Engel, R.W., and Copeland, D.H.: Protective Action of Stock Diets against the Cancer-Inducing Action of 2-Acetylaminofluorene in Rats, Cancer Res12:211-215, 1952.
8.
Tuba, J.; Rawlinson, H.E.; Fraser, M.S.; and Jeske, I.: Hyperplastic Nodules in Rat Mammary Glands Following the Feeding of 4-Acetylaminobiphenyl , Canad J Med Sci31:95-98, 1953.
9.
Ershoff, B.H. : Effects of Diets on Pituitary Tumor Induction by Estrogens, Exp Med Surg22:28-32, 1964.
10.
Ershoff, B.H. : Increased Survival of Liver-Fed Rats Administered Multiple Sublethal Doses of X-Irradiation, J Nutr47: 289-298, 1952.
11.
Ershoff, B.H. ; Bajwa, G.S.; Field , J.B.; and Bavetta, L.B.: Comparative Effects of Purified Diets and a Natural Food Stock Ration on the Tumor Incidence of Mice Exposed to Multiple Sublethal Doses of Total-Body X-Irradiation, Cancer Res29: 780-788, 1969.
12.
Ershoff, B.H. , and Graham, T.M.: Chronic Effects of Continuous Low-Level Gamma Radiation Upon B Vitamin Requirements, ASD Technical Report61-534, October 1961, pp 1-39.
13.
Greulich, R.C. , and Ershoff, B.H.: Delayed Effects of Multiple Sublethal Doses of Total Body X-Irradiation on the Periodontium and Teeth of Mice, J Dent Res40:1211-1224, 1961 .
14.
Ershoff, B.H. ; Bajwa, G.S.; Shapiro , M.; and Bernick, S.: Comparative Effects of a Purified Diet and Natural Food Stock Rations on the Periodontium of Mice Exposed to Multiple Sublethal Doses of Total Body X-Irradiation, J Dent Res46 :1051-1057, 1967 .
15.
Ershoff, B.H. , and Hershberg, D.: The Beneficial Effects of Yeast on the Cardiac Failure of Hyperthyroid Rats, Amer J Physiol145:16-22, 1945.
16.
Ershoff, B.H. : Comparative Effects of Liver and Yeast on Growth and Length of Survival of the Immature Thyroid-Fed Rat, Arch Biochem15:365-378, 1947.
17.
Ershoff, B.H. : Effects of the Fat Content of the Ration on the Antithyrotoxic Properties of B Vitamins and Liver Residue in the Hyperthyroid Rat, Metabolism2 :175-181, 1953.
18.
Bavetta, L.A. ; Bernick, S.; and Ershoff, B.: The Influence of Dietary Thyroid on the Bones and Periodontium of Rats on Total and Partial Tryptophan Deficiencies, J Dent Res36:13-20, 1957.
