Restricted accessResearch articleFirst published online 1970-04
Studies on the Biology of the Periodontium of Marmosets: IX. Effect of Parathyroid Hormone on the Alveolar Bone of Marmosets Pretreated with Fluoridated and Nonfluoridated Drinking Water
The alveolar bone of the marmoset is exceedingly vulnerable to the resorption induced by excessive amounts of parathyroid hormone. Inclusion of 50 ppm fluoride in the drinking water of the marmosets for five months resulted in a histologically measurable degree of protection against the bone-destroying proclivity of the hormone.
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References
1.
Bernstein, D.S. ; Sadowsky, N.; Hegsted , D.M.; Guri, C.D.; and Stare, F.J.: Prevalence of Osteoporosis in High- and Low-Fluoride Areas in North Dakota, JAMA198:499-504, 1966.
2.
Cohen, P., and Gardner, F.H.: Induction of Subacute Skeletal Fluorosis in a Case of Multiple Myeloma , New Eng J Med271:1129-1133, 1964 .
3.
Rich, C.; Einsinck, J.; and Ivanovich, P.: The Effects of Sodium Fluoride on Calcium Metabolism of Subjects with Metabolic Bone Diseases, J Clin Invest43:546-556, 1964.
4.
Rose, G.A.: A Study of the Treatment of Osteoporosis with Fluoride Therapy and High Calcium Intake, Proc Roy Soc Med58:436-440, 1965.
5.
Gron, P.; Mccann, H.G.; and Bern
6.
Stein, D.S.: Effect of Fluoride on Human Osteoporotic Bone Mineral: A Chemical and Crystallographic Study, J Bone Joint Surg48A:892-898, 1966.
7.
Zipkin, I.; McClure, F.J.; and Lee, W.A.: Relation of the Fluoride Content of Human Bone to Its Chemical Composition , Arch Oral Biol2:190-195, 1960.
8.
Dreizen, S.; Levy, B.M.; Bernick, S.; Hampton, J.K., JR.; and Kraintz, L.: Studies on the Biology of the Periodontium of Marmosets: III. Periodontal Bone Changes in Marmosets with Osteomalacia and Hyperparathyroidism, Israel J Med Sci3:731-738, 1967.
9.
RoHOLM, K.: Fluorine Intoxication. London : H. K. Lewis & Co. Ltd., 1937, p 275. 9. BERNICK, S., and ZIPKIN, I.: Histochemical Study of Bone in Hydrocortisone- and Fluoride-Treated Rats, J Dent Res 46: 1404-1411, 1967.
10.
Copp, D.H.: Parathyroid Hormone, Calcitonin and Calcium Homeostasis, in Talmage, R.V., and Belanger, L.F. (eds): Parathyroid Hormone and Thyrocalcitonin (Calcitonin) , New York: Excerpta Medica Foundation , 1968, pp 25-39.
11.
Neuman, W.F. , and Neuman, M.W.: The Chemical Dynamics of Bone Mineral , Chicago: The University of Chicago Press, 1958, p 97.
12.
ALWALL, N.: Studien über die Regulation vom Citronen-sauregehalt des Blutserums IV, Acta Med Scand 116:337-339, 1944. 13. L'HEUREUX, M.V., and ROTH, G.J.: Influence of Parathyroid Extract on Citric Acid of the Serum, Proc Soc Exp Biol Med 84: 7-9, 1953.
13.
Firschein, H.E. ; Neuman, W.F.; Martin , G.R.; and Mulryan, B.J.: Studies on the Mechanism of Action of the Parathyroid Hormone, in Pincus, G. (ed): Recent Progress in Hormone Research, Vol 15, New York: Academic Press, 1959, pp 427-448.
