Two studies were conducted in rats to investigate fluoride retention from a prenatal supplement and the influence of NaF and NaSn2F5 in prenatal supplements on dental caries. Fluoride retention, provided as NaF, was decreased by 38.2%. Prenatal NaSn2F5 reduced the incidence of dental caries by 80%.
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References
1.
Hennon, D.K. ; Stookey, G.K.; and Muhler, J.C.: The Clinical Anticariogenic Effectiveness of Supplementary Fluoride Vitamin Preparations: Results at the End of Three Years, J Dent Child33:3-12, 1966.
2.
Hennon, D.K. ; Stookey, G.K.; and Muhler, J.C.: The Clinical Anticariogenic Effectiveness of Supplementary Fluoride-Vitamin Preparations: Results at the End of Four Years, J Dent Child34:439-443, 1967.
3.
Margolis, F.J. ; Macauley, J.; and Fresh-Man, E.: The Effects of Measured Doses of Fluoride , Amer J Dis Child113:670-672, 1967.
4.
Stookey, G.K. : "Fluoride Therapy," in BERNIER, J.L., and MUHLER, J.C., Improving Dental Practice through Preventive Measures, chap 5, St. Louis, Mo.: C. V. Mosby Co., 1966.
5.
Feltman, R., and Kosel, G.: Prenatal and Postnatal Ingestion of Fluoride-14 Years of Investigation-Final Report, J Dent Med16:190-198, 1961.
6.
Blayney, J.R., and Hill, I.N.: Evanston Dental Caries Study: XXIV. Prenatal Fluorides-Value of Water-Born Fluorides during Pregnancy, JADA69:291-294, 1964.
7.
Katz, S., and Muhler, J.C.: Prenatal Fluoride and Dental Caries Experience in Deciduous Teeth , JADA76:305-311, 1968.
8.
Carlos, J.P.; Gettelsohn, A.M.; and Haddon, W., JR.: Caries in Deciduous Teeth in Relation to Maternal Ingestion of Fluoride, Pub Health Rep77:658-660, 1962.
9.
Weddle, D.A., and Muhler, J.C.: The Effects of Inorganic Salts on Fluorine Storage in the Rat, J Nutr54:437-444, 1954.
10.
Muhler, J.C. , and Weddle, D.A.: Utilization of Fluorine for Storage in the Rat When Administered in Milk, J Nutr55: 347-352, 1955.
11.
Weddle, D.A. , and Muhler, J.C.: The Metabolism of Different Fluorides in the Rat: I. Comparison between Sodium Fluoride, Sodium Silicofluoride, and Stannous Fluoride, J Dent Res36:386-390, 1957.
12.
Wagner, M.J. , and Muhler, J.C.: The Effect of Calcium and Phosphorus on Fluoride Absorption, J Dent Res39:49-52, 1960.
13.
Stookey, G.K. ; Crane, D.B.; and Muhler, J.C.: Further Studies on Fluoride Absorption , Proc Soc Exp Biol Med115:295-298, 1964.
14.
Lawrenz, M. , and Mitchell, H.H.: Effect of Dietary Calcium and Phosphorus on the Assimilation of Dietary Fluorine, J Nutr22:91-101, 1941.
15.
Scow, R.O.: Total Pancreatectomy in the Rat: Operation, Effects, and Postoperative Care , Endocrinology60:359-367, 1957.
16.
Muhler, J.C. , and Day, H.G.: Effects of Stannous Fluoride, Stannous Chloride, and Sodium Fluoride on the Incidence of Dental Lesions in Rats Fed a Caries-Producing Diet, JADA41:528-535, 1950.
17.
Sognnaes, R.F. : Caries-Conductive Effect of a Purified Diet When Fed to Rodents during Tooth Development, JADA37 :676-692, 1948.
18.
Wynn, W.; Haldi, J.; Shaw, J.H.; and Sognnaes, R.F.: Difference in Caries-Producing Effects of Two Purified Diets Containing the Same Amount of Sugar, J Nutr50:267-274, 1953.
19.
Shaw, J.H.: Caries-Producing Factors: A Decade of Dental Research-Project No. 3 of the Sugar Research Foundation, Inc., JADA55:785-789, 1957.
20.
Watson, B.F. , and Muhler, J.C.: Relationship between Maternal Ingestion of Carbohydrate in the Rat and Dental Caries Susceptibility of the Progeny , J Dent Res38:618-623, 1959.
21.
Muhler, J.C. ; Stookey, G.K.; and Beck, C.W.: Preparation and Properties of Sodium Pentafluorostannite , J Dent Res46:380-383, 1967.
