This paper describes the individual variations in the length and area of the basement membrane and in the volume of the epithelium. The wide variations in the area of the basement membrane and the total epithelial cell population necessitates the introduction of a new method for calculating mitotic activity and turnover rate. A new mitotic index system is suggested.
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References
1.
Montagna, W.: "Morphology of the Aging Skin: The Cutaneous Appendages," in Montagna, W., (ed.): Advances in Biology of Skin, Vol. VI, Oxford: Pergamon Press, 1965.
2.
Wentz, F.M.; Maier, A.W.; and Orban, B.: Age Changes and Sex Differences in the Clinically "Normal" Gingiva, J Periodont23:13-24, 1952.
3.
Shklar, G.: The Effects of Aging Upon Oral Mucosa, J Invest Derm47:115-120, 1966.
4.
Emslie, R.D. , and Weinmann, J.P.: The Architectural Pattern of the Boundary Between Epithelium and Connective Tissue of the Gingiva in the Rhesus Monkey , Anat Rec105:35-57, 1949.
5.
Emslie, R.D. : The Architectural Pattern of the Boundary Between Epithelium and Connective Tissue of the Gingiva, Proc Roy Soc Med44:859-863, 1951.
6.
Karring, T., and Löe, H.: The Three-Dimensional Concept of the Epithelium-Connective Tissue Boundary of Gingiva. In preparation.
7.
Marwah, A.S. ; Weinmann, J.P.; and Meyer, J.: Effect of Chronic Inflammation on the Epithelial Turnover of the Human Gingiva, Arch Path69:147-153, 1960.
8.
Loe, H.: The Gingival Index, the Plaque Index and the Retention Index Systems, J Periodont38:610-616, 1967.
9.
Karring, T., and Löe, H.: A Method for the Quantitation of the Epithelium-Connective Tissue Interface . In preparation.
10.
Minot, G.S.: The Problems of Age, Growth and Death: A Study of Cytomorphosis, based on Lectures at The Lowell Institute, March 1907, New York/London: G. P. Putnam Sons, 1908, p 204.
11.
Mühlemann, H.R.; Ebneter, M.; and Rupf, W.: Diurnal Variation in Mitotic Activity of Oral and Corneal Epithelium in Colchicinized Albino Rats, Helv Odont Acta3:30-34, 1959.
12.
Meyer, J.; Marwah, A.S.; and Weinmann, J.P.: Mitotic Rate of Gingival Epithelium in Two Age Groups, J Invest Derm27: 237-247, 1946.
13.
Kiljunen, A. : Mitotic Activity in Normal and Malignant Epidermal Tissue of The Rat, Acta Path et Microbiol Scand, Suppl 112, 1956, p 101.
14.
Randers Hansen, E.: Mitotic Activity and Mitotic Duration in Tongue Epithelium of Rats, Odont T75:473-479, 1967.
15.
Gargiulo, A.W. ; Wentz, F.M.; and Orban, B.: Mitotic Activity of Human Oral Epithelium Exposed to 30% Hydrogen Peroxide, Oral Surg14 :474-492, 1961.
16.
Hayes, R.L. ; Silberkweit, M.; Soni, N.N.; and Simpson, T.H.: Pattern of Mitotic Activity and Cell Densities in Normal Gingival Epithelium of Children, J Dent Res43:217-223, 1964.
17.
Soni, N.N.; Silberkweit, M.; and Hayes, R.L.: Pattern of Mitotic Activity and Cell Densities in Human Gingival Epithelium , J Periodont36:15-21, 1965.
18.
Silberkweit, M.; Soni, N.N.; and Hayes, R.L.: Pattern of Mitotic Activity and Cell Densities in the Epithelium of Inflamed Gingiva of Children, J Dent Res42 :1503-1510, 1963.
19.
Trott, J.R. , and Gorenstein, S.L.: Mitotic Rates in the Oral and Gingival Epithelium of the Rat, Arch Oral Biol8: 425-434, 1963.
20.
Randers Hansen, E.: Mitotic Activity in the Oral Epithelium of the Rat: Variations according to Age and Time of Day, Odont T74:196-201, 1966.
