The concentration of lithium after oral administration in human parotid saliva, submaxillary saliva, and serum was determined; salivary concentrations were several times that of serum. Lithium in unstimulated saliva was directly proportional to serum concentration; lithium in stimulated parotid saliva tended to be a negative function of flow rate.
Get full access to this article
View all access options for this article.
References
1.
Coppen, A.; MALLEsoN, A.; and SHAw, D.M.: Effects of Lithium Carbonate on Electrolyte Distribution in Man, Lancet1: 682-683, 1965.
2.
Hodgkin , A.L.: The Effect of Potassium on the Surface Membrane of an Isolated Axon, J Physiol (London)106:319-340, 1947.
3.
Schlagenhauf, G.; Tupin, J.; and White, R.B.: Use of Lithium Carbonate in the Treatment of Manic Psychoses, Amer J Psychiat123:201-207, 1966.
4.
Shannon, I.L. ; Prigmore, J.R.; and Chauncey , H.H.: Modified Carlson-Crittenden Device for the Collection of Parotid Fluid, J Dent Res41:778-783, 1962.
5.
Block, P.L., and Brottman, S.A.: A Method of Submaxillary Salivary Collection without Cannulation, New York Dent J28: 116-118, 1962.
6.
Mason, D.K.; Boyle, J.A.; Harden, R.M.; Duncan, A.M.; and Greig, W.R.: Influence of Flow Rate on the Concentration of Uric Acid in Human Parotid and Submandibular Saliva, J Dent Res45 :1439-1444, 1966.
7.
Burgen, A.S.V.: Secretion of Non-Electrolytes in the Parotid Saliva, J Cell Comp Physiol48:113-138, 1956.
8.
Windeler, A.S., and Shannon, I.L.: Effect of Flow Rate on Parotid Fluid Calcium, Magnesium and Protein Concentrations in the Human, USAF Aerospace Med1-5, 1967.
9.
Burgen, A.S.V., and Emmelin, N.G.: Physiology of the Salivary Glands, London: Edward Arnold & Co., 1961, pp 149-152.
10.
Shannon, I.L. : Parotid Fluid Flow Rate, Parotid Fluid and Serum Inorganic Phosphate Concentrations as Related to Dental Caries Status in Man, J Dent Res43 :1029-1038, 1964.
11.
Burgen, A.S.V. : Secretion of Lithium in Saliva, Can J Biochem36:409-411, 1958.