An extract of guinea pig thyroid gland produced a mild hypocalcemia indicative of the presence of thyrocalcitonin when administered intravenously to nongravid guinea pigs. Extract-induced hypocalcemia in gravid guinea pigs resulted in a rise in fetal plasma calcium values at the end of four hours.
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References
1.
Hirsch, P.F. ; Gauthier, G.F.; and Mun-Son , P.L.: Thyroid Hypocalcemic Principle and Recurrent Laryngeal Nerve Injury as Factors Affecting the Response to Parathyroidectomy in Rats, Endocrinology73: 244-252, 1963.
2.
Gittes, R.F. ; Wells, S.A.; and Irvin, G.L.: A Role for the Parathyroid Glands in Calcium Homeostasis, J Urol97 :1082-1089, 1967.
3.
Bawden, J.W. ; Wolkoff, A.S.; and Flowers, C.E.: Maternal-Fetal Blood Calcium Relationships in Sheep, Obstet Gynec25: 548-552, 1965.
4.
Bawden, J.W. , and Wolkoff, A.S.: Fetal Blood Calcium Responses to Maternal Calcium Infusion in Sheep, Amer J Obstet Gynec99:59-60, 1967.
5.
Burnette, J.C. ; Simpson, D.M.: CHANDLER, D.C., JR.; and BAWDEN, J.W. : Fetal Blood Calcium Response to Maternal Parathyroid Extract and Vitamin D Administration in Guinea Pigs, J Dent Res47:444-446, 1968.
6.
Greeson, C.D. ; Crawford, E.G., JR.; Chandler , D.C., JR.; and Bawden, J.W.: Fetal Calcium Response to Maternal Hypercalcemia in Guinea Pigs, J Dent Res46: 447-449, 1968.
7.
Mull, J.W., and Bill, A.H.: Calcium and Inorganic Phosphorus Content of Prenatal and Postpartum Serum , Amer J Obstet Gynec23:807-814, 1932.
8.
Simpson, D.M. ; Burnette, J.C.; and Bawden, J.W.: Maternal-Fetal Blood Tetracycline Levels in Guinea Pigs, J Oral Ther6:403-408, 1967.
9.
Radin, N., and Gramza, A.L.: Differential Spectrophotometric Determination of Calcium, Clin Chem10:704-720, 1964.
10.
Stahl, P.D. , and Kenney, A.D.: Thyrocalcitonin in the Dog: Serum Calcium and Phosphorus Responses, Endocrinology81: 661-666, 1967.
11.
Hallman, N. , and Salmi, J.: On Plasma Calcium in Cord Blood and in the Newborn, Acta Paediat Scand42:126-129, 1953.
