Levels of parenterally injected tetracycline in the blood and dental pulps of rats were compared, and pulp levels were found to be prolonged. Temporary fixation of tetracycline was demonstrated in the dentin walls of the pulp cavities of vital human, canine, and bovine teeth. Prolonged levels in the pulp probably are maintained from this antibiotic deposit.
Get full access to this article
View all access options for this article.
References
1.
Spreter V.Kreudenstein, T.; Stüben, J.; and Knothe, H.: Experimentelle Untersuchungen zum Nachweiss des Übertritts von Tetrazyklin aus dem Blut in den Dentinliquor, Deutsch Zahnaerztl Z12:1691-1693, 1957.
2.
Grove, D.C., and Randall, W.A.: Assay Methods of Antibiotics; A Laboratory Manual, New York: Medical Encyclopedia Inc., Antibiotic Monographs , 1957.
3.
Haldi, J., and John, K.: Sulfanilamide and Penicillin in the Pulp Fluid of the Dog Following Administration of These Compounds, J Dent Res44:1386-1388, 1965.
4.
Tapp, E.: Tetracycline Labelling Methods of Measuring the Growth of Bones in the Rat , J Bone Joint Surg [Brit]48:517-525, 1966.
5.
Spreter V.Kreudenstein, T.: Vergleich der Elimination aus Blut und Dentinliquor bei verschiedenen antibiotischen Mitteln, Klin Wschr35:591-592, 1957.
6.
Harris, H.W. ; Jackson, R.H.; and Jowsey, J.: The In Vivo Distribution of Tetracyclines in Canine Bone, J Bone Joint Surg [Brit]44:1308-1320, 1962.
7.
Antalovská, Z., and Záchvej, P.: Fluorescence tetracyklinovych antibiotik v lidske zubni dreni, Czas Stomat67:403-407, 1967.
8.
Svejda, J.: Hojeni poranene dřeně telecich zubu, Czas Stomat60:243-248, 1960.
