The mean reduction in oxygen uptake of incisor pulp from 142 hypophysectomized rats was 10.2%. This figure is significant in the negative sense, in that it demonstrates a relatively undisturbed physiologic pattern of pulp. This finding coincides with the histologic findings of others, that hypophysectomy disturbs the enamel organ, resulting in a lack of enamel formation and eruption, but spares the dentin-forming properties of pulp, resulting in the intrapulpal folding of dentin.
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