Selective Colorimetric Determination of Local Anesthetics Containing a Tertiary Amine

Feldmann, E.G. The Colorimetric Determination of Certain Local Anesthetics with Sodium 1,2-Naphthoquinone-4-sulfonate, J. Am. Pharm. Assoc., Sci. Ed., 48:197, 1959.

Feldmann, E.G. , and Koehler, H.M. The Colorimetric Determination of Lidocaine with cis-Aconitic Anhydride, J. Am. Pharm. Assoc., Sci. Ed. , 48:549, 1959.

Sass, S. , Kaufman, J.J. , Cardenas, A.A. , and Martin, J.J. Colorimetric Estimation of Tertiary and Quaternary Amines, Anal. Chem., 30:529, 1958.

Eissner, W. Colorimetric Determination of Novocaine and Anesthesine with β-Naphthol, Arch. Pharm., 268:322, 1930.

Seydlitz, H. Colorimetric Determination of Procaine and Para-aminobenzoic Acid in Mixtures, Svenska Farm. Tidskr., 50:65, 1946.

Ting, K.S. , Coon, J.M. , and Conway, A.C. Spectrophotometric Method for Determination of Procaine and Para-aminobenzoic Acid, J. Lab. Clin. Med. , 34:822, 1949.

Oelssner, W. Colorimetric Determination of Procaine and Para-aminobenzoic Acid , Pharmazie, 7:133,1952.

Chakravarti, S.N. , and Roy, M.B. New Colorimetric Test for Procaine and Primary Amines, Analyst, 62:603, 1937.

Yamagishi, M. Colorimetric Determination of Procaine , Ann. Repts. Takeda Research Lab., 10:35, 1951.

Riegel, E.R. , and Williams, J.F. New Color Reaction for Procaine and Some Other Local Anesthetics and Its Application to the Determination of Procaine, J. Am. Chem. Soc., 48:2871, 1926.

Jannke, P.J. The Assay of Benzocaine, Pharm. Arch., 16:25, 1945.

Vallejo, S.R. The Determination of Aminated Drugs by Diazotization , Rev. quim. farm. (Santiago, Chile), 8:5, 1951.

Pratt, E. , L. Spectrophotometric Titrations with Nitrous Acid. I. The Estimation of Procaine Hydrochloride, Propoxycaine Hydrochloride, and Tetracaine Hydrochloride , J. Am. Pharm. Assoc., Sci. Ed., 46:724, 1957.

Mitchell, J., JR. , Hawkins, W. , and Smith, D.M. Analytical Procedures Employing Karl Fischer Reagent. XI. The Determination of Primary Plus Secondary Amines, J. Am. Chem. Soc., 66:782, 1944.

Ogg, C.L. , Porter, W.L. , and Willits, C.O. Determining the Hydroxyl Content of Certain Organic Compounds. Macro- and Semimicromethods, Ind. Eng. Chem., Anal. Ed., 17 :394, 1945 ; as extended in Siggia, S. Quantitative Organic Analysis via Functional Groups, chap. 10, pp. 107, 108, 117. 2d ed. New York: John Wiley & Sons, 1954.

Koehler, H.M. , and Feldmann, E.G. Qualitative Identification of Local Anesthetics in Their Dosage Forms, Anal. Chem., 32:28, 1960.

Duke, F.R. Metallo-organic Complexes in Organic Analysis: Some Qualitative Tests for Amines, Ind. Eng. Chem., Anal. Ed., 17:196, 1945.