Comparative cross-cultural studies of psychopathology were reviewed in relation to the parameters of incidence, mode of manifestation, patterning, response to treatment, and outcome. A general model was proposed of regarding such differences as the joint function of subject, observer, setting, community, and instrument factors. The findings surveyed, even in their present nondefinitive state, favor the notion of cultural plasticity of psychopathology and, moreover, converge in suggesting that psychopathology represents a caricature and an exaggeration of culturally shared adaptive patterns of behavior. For a more conclusive examination of this possibility, concurrent research on normal and abnormal subjects drawn from several cultures was proposed and a number of specific modes of implementing this objective were presented.
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