A novel hydroxyapatite-wollastonite/silk fibroin (AW/SF) composite was prepared for bone repair and replacement by a modified coprecipitation method. The wollastonite powders introduced in the composite were sintered with full crytallinity and ground to the diameter of 30–50 nm. The FT-IR and XRD analyses showed that the silk fibroin, wollastonite, and hydroxyapatite co-existed in the composite, but the newly formed hydroxyapatite had low crystallinity ascribing to the low temperature procedure. The composite exhibited both higher compressive strength (84.4 MPa) and Barcol hardness (48.5) than the hydroxyapatite/silk fibroin (HA/SF) composite without any wallostonite involved. And the composite in this work showed excellent bioactivities while held in simulated body fluid (SBF).
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