Various aspects of compliance behavior were investigated in connection with a genetic screening clinic designed to rest for the Tay-Sachs gene in a specified target population. Selected antecedents of compliance were combined into an integrativeframework based on data obtainedfrom 392 members of the Jewish community in Vancouver, Canada. Drawing on and extending several "health belief models" proposed in the literature, it was hypothesized that compliance would be a function of several endogenous (social responsibility, susceptibility, family planning, family discussion, and objective knowledge of the disease) and exogenous (age, education, sex, and exposure to a carrier) variables. A path-analytic investigation of the hypothesized linkages suggested that a more parsimonious model of compliance determinants may be adequate.
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