Three studies used humans to simulate the functions of science information systems. The simulated systems were made available to biochemist users to fulfill their information needs. The requesting behavior of the users and of the simulated system elements in response to requests was measured with respect to a number of variables: (e.g., frequency, time and type of requests). The results are interpreted in terms of their implications for the design of improved science information services and systems and the functional properties that these systems should have to meet user requirements.
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