The increasing complexity of cancer chemotherapy makes it mandatory that pharmacists be familiar with these highly toxic agents. This column reviews various issues related to the preparation, dispensing, and administration of cancer chemotherapy, both commercially available and investigational.
Get full access to this article
View all access options for this article.
References
1.
CzuczmanM.S., Grillo-LopezA.J., WhiteC.A.Treatment of patients with low-grade B-cell lymphoma with the combination of chimeric anti-CD20 monoclonal antibody and CHOP chemotherapy. J Clin Oncol.1999; 17: 268–76.
2.
VoseJ.M., LinkB.K., GrossbardM.L.Phase II study of rituximab in combination with CHOP chemotherapy in patients with previously untreated, aggressive non-Hodgkin's lymphoma. J Clin Oncol.2001; 19: 389–97.
3.
CoiffierB., LepageE., GaulardP.Prognostic factors affecting the efficacy of rituximab plus CHOP (R-CHOP) therapy in elderly patients with diffuse large B-cell lymphoma (DLCL): Results of a randomized GELA trial. Proc Am Soc Clin Oncol [CD ROM version 2001]. Alexandria, VA: American Society of Clinical Oncology; 2001. Abstract 1131.
4.
TrisselL., ZhangY., CohenM.The stability of diluted vincristine sulfate used as a deterrent to inadvertent intrathecal injection. Hosp Pharm.2001; 36: 740–5.
5.
HeskethP.J., KrisM.G., GrunbergS.M.Proposal for classifying the acute emetogenicity of cancer chemotherapy. J Clin Oncol.1997; 15: 103–9.
6.
American Society of Health-System Pharmacists.ASHP therapeutic guidelines on the pharmacologic management of nausea and vomiting in adult and pediatric patients receiving chemotherapy or radiation therapy or undergoing surgery. Am J Health Syst Pharm.1999; 56: 729–64.
7.
National Comprehensive Cancer Network.NCCN antiemesis practice guidelines. The Complete Library of NCCN Oncology Practice Guidelines [CD-ROM, version 2000].Rockledge, PA: National Comprehensive Cancer Network; 2000.
8.
GrallaR.J., OsobaD., KrisM.G.Recommendations for the use of antiemetics: evidence-based, clinical practice guidelines. J Clin Oncol.1999; 17: 2971–94.
9.
StillwellT.J., BensonR.C.Cyclophosphamide-induced hemorrhagic cystitis: A review of 100 patients. Cancer.1988; 61: 451–7.
