Management of Adult Heart Failure: Bolus versus Continuous Infusion Loop Diuretics,A Review of the Literature

Abstract

In an aging population, decompensated heart failure accounts for a significant number of hospital admissions. The standard management for edema and congestion associated with heart failure is loop diuretic therapy. Traditionally, bolus-dosed furosemide has been used to manage the edema and congestion associated with heart failure. However, diuretic resistance can occur with bolus dosing, resulting in inadequate diuresis and further hemodynamic instability. Based on current literature, furosemide given by continuous infusion may now be the preferred agent and route for diuretic refractory heart failure. This article reviews the literature that compares bolus versus continuous infusion loop diuretics in adult heart failure.