This paper presents a report on a child with Wiskott-Aldrich syndrome. The clinical picture and laboratory findings are characteristic of this disease. The prevailing symptoms have included recurrent respiratory and alimentary tract infections, seborrhic dermatitis-type skin lesions, and thrombocytopenia. Humoral and cellular immunological disturbances have been noted, and the pedigree pattern is very characteristic.
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References
1.
Meuwissen H. , Bortin M., Bach F., et al. Long-term survival after bone marrow transplantation: a 15-year follow-up report of a patient with Wiskott-Aldrich syndrome. J Pediatr1984;105:365-9.
2.
Parkman R., Rappeport J., Geha R., et al. Complete correction of the Wiskott-Aldrich syndrome by allogenic bone marrow transplantation. N Engl J Med1978;298:921-7.
Miller DR, Baehner RL, McMillan CWBlood diseases of infancy and childhood. St. Louis: CV Mosby, 1984.
5.
Lum L., Tubergen D., Corash L., et al. Splenectomy in the management of the thrombocytopenia of the Wiskott-Aldrich syndrome. N Engl J Med1980 ;302:892-5.
6.
Parkman R., Remold-O'Donnell E., Kenney D., et al. Surface protein abnormalities in lymphocytes and platelets from patients with Wiskott-Aldrich syndrome. Lancet1981;2:1387-9.